Abstract Background Arginine biosynthesis in Corynebacterium glutamicum consists of eight
enzymatic steps, starting with acetylation of glutamate, catalysed by N-acetylglutamate …

Arginine biosynthesis in Corynebacterium glutamicum proceeds via a pathway that is
controlled by arginine through feedback inhibition of NAGK, the enzyme that converts N …

Abstract Objective In Corynebacterium crenatum, the adjacent D311 and D312 of N-acetyl-L-
glutamate kinase (NAGK), as a key rate-limiting enzyme of L-arginine biosynthesis under …

We recently proposed a metabolic engineering strategy for l-ornithine production based on
the hypothesis that an increased intracellular supply of N-acetylglutamate may further …

Abstract Corynebacterium crenatum SYPA5-5, an l-arginine high-producer obtained through
multiple mutation-screening steps, had been deregulated by the repression of ArgR that …

N-acetyl glutamate kinase (NAGK) is a key enzyme in the synthesis of l-arginine that is
inhibited by its end product l-arginine in Corynebacterium glutamicum (C. glutamicum). In …

Major aspects of the pathway of de novo arginine biosynthesis via acetylated intermediates
in microorganisms must be revised in light of recent enzymatic and genomic investigations …

Abstract l-arginine is a semi-essential amino acid that is broadly used as food additives and
pharmaceutical intermediates. The synthesis of l-arginine is restricted by complex metabolic …

N-Acetyl-l-glutamate kinase (EC 2.7. 2.8) is first committed in the specific l-arginine pathway
of Corynebacterium sp. A limited increase of l-arginine production for the arg B …

A cluster of arginine biosynthetic genes of Corynebacterium glutamicum ATCC 13032,
comprising argJ, argB and argD as well as part of argC and argF, has been cloned by …