Introduction Interleukin-6 (IL-6) is elevated during acute myocardial infarction (AMI)
particularly after reperfusion with primary percutaneous coronary intervention (PPCI). Higher …

BACKGROUND: Interleukin-6 (IL-6) is elevated during Myocardial Infarction (MI) and higher
levels are associated with adverse outcomes. IL-6 signalling may be mediated by binding to …

Abstract Aims Interleukin-6 receptor (IL-6R) signalling has been suggested to play a causal
role in the development and outcome of coronary heart disease (CHD). The aim of this study …

Summary Interleukin (IL)-6 is an emerging therapeutic target in myocardial infarction (MI). IL-
6 has 2 distinct signaling pathways: trans-signaling, which mediates inflammation, and …

Background Interleukin-6 (IL-6) levels are upregulated in myocardial infarction. Recent data
suggest a causal role of the IL-6 receptor (IL-6R) in coronary heart disease. We evaluated if …

Background Acute myocardial infarction (AMI) harbours marked inflammatory components.
While cytokines of the same family have been causally related to patient outcome, the role of …

Biomarkers such as interleukin-6 (IL-6), soluble interleukin-6 receptor (sIL-6R), and high
sensitive C-reactive protein (hsCRP) have been reported to be elevated in acute myocardial …

Background: Prompt myocardial revascularisation with percutaneous coronary intervention
(PCI) reduces infarct size and improves outcomes in patients with acute ST segment …

Background and aims Myocardial infarction triggers an inflammatory response involved in
cardiac repair. We studied the association of the interleukin 6 (IL-6) cascade with infarct size …

Interleukin 6 (IL-6) is a pleiotropic cytokine involved in both inflammatory reaction and
myocardial response to stress. Its effects largely depend on the concentration of the soluble …