Brain amyloid β, cerebral small vessel disease, and cognition: A memory clinic study
FN Saridin, S Hilal, SG Villaraza, A Reilhac… - Neurology, 2020 - AAN Enterprises
Objective To evaluate the association between brain amyloid β (Aβ) and cerebral small
vessel disease (CSVD) markers, as well as their joint effect on cognition, in a memory clinic …
vessel disease (CSVD) markers, as well as their joint effect on cognition, in a memory clinic …
Effects of amyloid and vascular markers on cognitive decline in subcortical vascular dementia
Objective: To determine the independent and synergistic effects of amyloid and small vessel
disease (SVD) burden on longitudinal cognitive decline in patients with subcortical vascular …
disease (SVD) burden on longitudinal cognitive decline in patients with subcortical vascular …
The impact of amyloid-β or tau on cognitive change in the presence of severe cerebrovascular disease
Background: As Alzheimer's disease (AD) and cerebral small vessel disease (CSVD)
commonly coexist, the interaction between two has been of the considerable interest …
commonly coexist, the interaction between two has been of the considerable interest …
Effects of cerebrovascular disease and amyloid beta burden on cognition in subjects with subcortical vascular cognitive impairment
Cerebrovascular disease (CVD) and amyloid burden are the most frequent pathologies in
subjects with cognitive impairment. However, the relationship between CVD, amyloid …
subjects with cognitive impairment. However, the relationship between CVD, amyloid …
Vascular burden score impacts cognition independent of amyloid PET and MRI measures of Alzheimer's disease and vascular brain injury
Background/Objective: To determine the impact of vascular burden on rates of decline in
episodic memory and executive function. We hypothesize that greater vascular burden will …
episodic memory and executive function. We hypothesize that greater vascular burden will …
[HTML][HTML] Distinct amyloid distribution patterns in amyloid positive subcortical vascular cognitive impairment
H Jang, JY Park, YK Jang, HJ Kim, JS Lee, DL Na… - Scientific reports, 2018 - nature.com
Amyloid-β (Aβ) and cerebral small vessel disease (CSVD) commonly coexist. They can
occur independently by chance, or may interact with each other. We aimed to determine …
occur independently by chance, or may interact with each other. We aimed to determine …
Vascular burden and cognition: Mediating roles of neurodegeneration and amyloid PET
It remains unclear to what extent cerebrovascular burden relates to amyloid beta (Aβ)
deposition, neurodegeneration, and cognitive dysfunction in mixed disease populations with …
deposition, neurodegeneration, and cognitive dysfunction in mixed disease populations with …
[HTML][HTML] CSF biomarkers and neuropsychological profiles in patients with cerebral small-vessel disease
Despite existing criteria, differential diagnosis of Vascular Dementia (VD) and Alzheimer's
disease (AD) remains difficult. The aim of this study is to figure out cognitive and biomarker …
disease (AD) remains difficult. The aim of this study is to figure out cognitive and biomarker …
[HTML][HTML] White matter lesions may be an early marker for age-related cognitive decline
Background Research suggests that cerebral small vessel disease (CSVD), amyloid, and
pTau contribute to age-related cognitive decline. It remains unknown how these factors …
pTau contribute to age-related cognitive decline. It remains unknown how these factors …
Perivascular spaces contribute to cognition beyond other small vessel disease markers
Objective To cross-sectionally relate multiple small vessel disease (SVD) neuroimaging
markers to cognition among older adults. Methods Vanderbilt Memory & Aging Project …
markers to cognition among older adults. Methods Vanderbilt Memory & Aging Project …