Objective To determine whether MRI-based cerebrovascular reactivity (CVR) can predict
cognitive performance independently of Alzheimer pathologic markers, we studied the …

Background: Alzheimer's disease (AD) frequently co-occurs with other brain pathologies.
Recent studies suggest there may be a mechanistic link between AD and small vessel …

Background: Cerebral small vessel disease (SVD) and Alzheimer's disease pathology,
namely amyloid-(A) deposition, commonly co-occur. Exactly how they interact remains …

Neuropsychiatric symptoms (NPS) affect the quality of life of patients with dementia and
increase the burden on caregivers. We aimed to evaluate how small vessel disease (SVD) …

Background: We tested our hypothesis that the white matter network might mediate the effect
of amyloid and small vessel disease (SVD) on cortical thickness and/or cognition. Methods …

Objective To investigate the relationship between enlarged perivascular spaces (EPVS) and
measures of Alzheimer disease (AD), small vessel disease (SVD), cognition, vascular risk …

While cerebrovascular disease can be observed in vivo using MRI, the multiplicity and
heterogeneity in the mechanisms of cerebrovascular damage impede accounting for these …

Background We investigated the independent effects of Alzheimer's disease (AD) and
cerebrovascular disease (CVD) pathologies on brain structural changes and cognition …

Cerebral small vessel disease (CSVD) occurs often in memory clinic patients. Apart from
cognitive deficits, these patients can express physical decline, which predicts adverse health …

Background: White matter hyperintensities (WMH) were shown to predict cognitive decline
following stroke or transient ischemic attack (TIA). However, WMH are only one among other …