Current treatment for Staphylococcus aureus infections relies heavily upon the cell wall
synthesis inhibitor antibiotics such as penicillin, oxacillin, vancomycin and teicoplanin …

Phenol-soluble modulins (PSMs) and Staphylococcal protein A (SpA) are key virulence
determinants for community-associated methicillin-resistant Staphylococcus aureus (CA …

NsaS is one of four intramembrane histidine kinases (HKs) in Staphylococcus aureus that
mediate the pathogen's response to membrane active antimicrobials and human innate …

Background Staphylococcus aureus is a major human pathogen and strains resistant to
existing treatments continue to emerge. Development of novel treatments is therefore …

The increasing prevalence of antimicrobial-resistant Staphylococcus aureus strains,
especially methicillin-resistant S. aureus (MRSA), poses a threat to successful antibiotic …

The overuse of antibiotics in humans and livestock has driven the emergence and spread of
antimicrobial resistance and has therefore prompted research on the discovery of novel …

The genetic plasticity of Staphylococcus aureus has facilitated the evolution of many virulent
and drug-resistant strains. Here we present the sequence of the 2.74 Mbp genome of S …

The emergence of drug-resistant bacteria coupled with the limited discovery of novel
chemical scaffolds and druggable targets inspires new approaches to antibiotic …

The virulence of Staphylococcus aureus is essentially determined by cell wall associated
proteins and secreted toxins that are regulated and expressed according to growth phases …

Staphylococcus aureus is a versatile pathogen that can survive in diverse host
environments. This versatility depends on its ability to sense nutrients and respond by …