Cocaine elevates dopamine (DA) in the nucleus accumbens (NAc) by blocking the uptake of
DA through the DA transporter (DAT). It is commonly believed that the reinforcing properties …

Cocaine produces its reinforcing effects primarily by inhibiting the dopamine transporter
(DAT) at the level of presynaptic terminals and increasing extracellular levels of dopamine …

The goal of this review is to describe what the voltammetry technique tells us about cocaine–
dopamine transporter (DAT) interactions and the subsequent changes in extracellular …

The dopamine (DA) uptake/clearance properties of the DA transporter (DAT) in the core and
shell of the nucleus accumbens were measured usingin vivoelectrochemical recordings …

Selective blockers of the norepinephrine transporter (NET) inhibit dopamine uptake in the
prefrontal cortex. This suggests that dopamine in this region is normally cleared by the …

A major theme of addiction research has focused on the neural substrates of individual
differences in the risk for addiction; however, little is known about how vulnerable …

Several classes of drugs bind to the dopamine transporter (DAT) with high affinity, but some
are weaker positive reinforcers than cocaine, suggesting that affinity for and occupancy of …

We investigated whether changes in the dopamine transporter in the nucleus accumbens or
striatum are involved in cocaine‐induced behavioral sensitization by using in vivo …

The reinforcing efficacy of cocaine is thought to stem from inhibition of the dopamine
transporter (DAT) and subsequent increases in extracellular dopamine concentrations in the …

Cocaine is a commonly abused central nervous system stimulant that enhances dopamine
(DA) neurotransmission through its ability to block dopamine transporters (DAT s). Recent …