Hypertonic saline resuscitation protects against kidney injury induced by severe burns in rats
CY Yuan, QC Wang, XL Chen, Q Wang, CS Sun… - Burns, 2019 - Elsevier
Background Proper fluid resuscitation can relieve visceral damage and improve survival in
severely burned patients. This study compared the effectiveness of resuscitation with 400 …
severely burned patients. This study compared the effectiveness of resuscitation with 400 …
Divergent effects of hypertonic fluid resuscitation on renal pathophysiological and structural parameters in rat model of lower body ischemia/reperfusion-induced …
The pathogenesis of acute kidney injury (AKI) is characterized by the deterioration of tissue
perfusion and oxygenation and enhanced inflammation. The purpose of this study was to …
perfusion and oxygenation and enhanced inflammation. The purpose of this study was to …
[HTML][HTML] A novel fluid resuscitation protocol: provide more protection on acute kidney injury during septic shock in rats
W Liu, XS Dong, YQ Sun, Z Liu - International Journal of Clinical …, 2014 - ncbi.nlm.nih.gov
Objective: To investigate the therapeutic effects of a novel fluid resuscitation protocol (early
fluid resuscitation plus 2% hydrogen inhalation) on acute kidney injury during septic shock …
fluid resuscitation plus 2% hydrogen inhalation) on acute kidney injury during septic shock …
Effect of 200 mEq/L Na+ hypertonic saline resuscitation on systemic inflammatory response and oxidative stress in severely burned rats
YX Sun, XS Wu, Z Gao, F Wang, S Liu… - Journal of Surgical …, 2013 - Elsevier
Background Excessive release of inflammatory mediators and oxidative stress play
important roles in the increased vascular permeability and systemic edema during the early …
important roles in the increased vascular permeability and systemic edema during the early …
Early fluid resuscitation with hypertonic solution in a rat crush injury model
XB Song, XL Zhou, SZ Ni, GF Yang, SF Tian, J Shan… - Shock, 2013 - journals.lww.com
Methods A rat model of crush injury was established. Rats were randomly divided into five
groups:(1) HHES group,(2) HTS group,(3) volume resuscitation group,(4) normal …
groups:(1) HHES group,(2) HTS group,(3) volume resuscitation group,(4) normal …
Hypertonic saline resuscitation detrimentally affects renal function and survival in dehydrated rats.
DS Malcolm, M Friedland, T Moore, J Beauregard… - Circulatory …, 1993 - europepmc.org
The purpose of our studies was to determine whether hypertonic (7.5%) saline (HTS)
resuscitation is effective in the setting of dehydration. We compared the effects of HTS (5 …
resuscitation is effective in the setting of dehydration. We compared the effects of HTS (5 …
[HTML][HTML] Effects of hydrogen-rich saline on early acute kidney injury in severely burned rats by suppressing oxidative stress induced apoptosis and inflammation
SX Guo, Q Fang, CG You, YY Jin, XG Wang… - Journal of translational …, 2015 - Springer
Background Early acute kidney injury (AKI) in severely burned patients predicts a high
mortality that is multi-factorial. Hydrogen has been reported to alleviate organ injury via …
mortality that is multi-factorial. Hydrogen has been reported to alleviate organ injury via …
[HTML][HTML] Enteral resuscitation with oral rehydration solution to reduce acute kidney injury in burn victims: evidence from a porcine model
BI Gómez, MK McIntyre, JM Gurney, KK Chung… - PloS one, 2018 - journals.plos.org
Intravenous (IV) resuscitation of burn patients has greatly improved outcomes and become a
cornerstone of modern burn care. However, the heavy fluids and vascular access required …
cornerstone of modern burn care. However, the heavy fluids and vascular access required …
Effect of dose of hypertonic saline on its potential to prevent lung tissue damage in a mouse model of hemorrhagic shock
Y Murao, W Loomis, P Wolf, DB Hoyt, WG Junger - Shock, 2003 - journals.lww.com
Recent studies have shown that hypertonic saline (HS) resuscitation can reduce
hemorrhage-induced lung damage by preventing neutrophil activation. In this study, we …
hemorrhage-induced lung damage by preventing neutrophil activation. In this study, we …
Kidney injury in a hemodilution model of hemorrhagic shock and fluid resuscitation
L Wang, F Pei, J Wu, B Ouyang, X Guan - The American Journal of the …, 2021 - Elsevier
Background Fluid therapy is indispensable in treating patients with hemorrhagic shock.
However, fluid overload correlates with kidney injury in patients with hemorrhagic shock. We …
However, fluid overload correlates with kidney injury in patients with hemorrhagic shock. We …