Background Proper fluid resuscitation can relieve visceral damage and improve survival in
severely burned patients. This study compared the effectiveness of resuscitation with 400 …

The pathogenesis of acute kidney injury (AKI) is characterized by the deterioration of tissue
perfusion and oxygenation and enhanced inflammation. The purpose of this study was to …

Objective: To investigate the therapeutic effects of a novel fluid resuscitation protocol (early
fluid resuscitation plus 2% hydrogen inhalation) on acute kidney injury during septic shock …

Background Excessive release of inflammatory mediators and oxidative stress play
important roles in the increased vascular permeability and systemic edema during the early …

Methods A rat model of crush injury was established. Rats were randomly divided into five
groups:(1) HHES group,(2) HTS group,(3) volume resuscitation group,(4) normal …

The purpose of our studies was to determine whether hypertonic (7.5%) saline (HTS)
resuscitation is effective in the setting of dehydration. We compared the effects of HTS (5 …

Background Early acute kidney injury (AKI) in severely burned patients predicts a high
mortality that is multi-factorial. Hydrogen has been reported to alleviate organ injury via …

Intravenous (IV) resuscitation of burn patients has greatly improved outcomes and become a
cornerstone of modern burn care. However, the heavy fluids and vascular access required …

Recent studies have shown that hypertonic saline (HS) resuscitation can reduce
hemorrhage-induced lung damage by preventing neutrophil activation. In this study, we …

Background Fluid therapy is indispensable in treating patients with hemorrhagic shock.
However, fluid overload correlates with kidney injury in patients with hemorrhagic shock. We …