Amiodarone and thyroid physiology, pathophysiology, diagnosis and management

RG Trohman, PS Sharma, EA McAninch… - Trends in cardiovascular …, 2019 - Elsevier
Although amiodarone is considered the most effective antiarrhythmic agent, its use is limited
by a wide variety of potential toxicities. The purpose of this review is to provide a …

Evaluation and treatment of amiodarone-induced thyroid disorders

D Ylli, L Wartofsky, KD Burman - The Journal of Clinical …, 2021 - academic.oup.com
Amiodarone is a class III antiarrhythmic drug containing 37% iodine by weight, with a
structure similar to that of thyroid hormones. Deiodination of amiodarone releases large …

Determinants and outcome of amiodarone‐associated thyroid dysfunction

S Ahmed, IC Van Gelder, ACP Wiesfeld… - Clinical …, 2011 - Wiley Online Library
Objective Amiodarone is frequently associated with thyroid dysfunction. Identifying
predictors for amiodarone‐associated thyroid dysfunction and assessing treatment outcome …

Amiodarone and the thyroid: a practical guide to the management of thyroid dysfunction induced by amiodarone therapy

CM Newman, A Price, DW Davies, TA Gray… - Heart, 1998 - heart.bmj.com
Amiodarone is a highly eVective agent for the prophylaxis and treatment of many cardiac
rhythm disturbances, ranging from paroxysmal atrial fibrillation to life threatening ventricular …

Effects of amiodarone therapy on thyroid function

J Cohen-Lehman, P Dahl, S Danzi, I Klein - Nature reviews …, 2010 - nature.com
Amiodarone is a benzofuran derivative approved for the treatment of cardiac arrhythmias.
Traditionally classified as a class III antiarrhythmic agent, amiodarone possesses …

Amiodarone and the thyroid: a 2012 update

F Bogazzi, L Tomisti, L Bartalena… - Journal of …, 2012 - Springer
Amiodarone-induced thyroid dysfunction occurs in 15–20% of amiodarone-treated patients.
Amiodarone-induced hypothyroidism (AIH) does not pose relevant problems, is easily …

Amiodarone and the thyroid

S Basaria, DS Cooper - The American journal of medicine, 2005 - Elsevier
Among the drugs affecting the thyroid gland, no drug has puzzled, and at the same time
fascinated, endocrinologists more than amiodarone. Amiodarone is a potent class III anti …

[HTML][HTML] Risk factors for amiodarone-induced thyroid dysfunction in Japan

S Kinoshita, T Hayashi, K Wada, M Yamato… - Journal of …, 2016 - Elsevier
Background Amiodarone is associated with a number of significant adverse effects,
including elevated transaminase levels, pulmonary fibrosis, arrhythmia, and thyroid …

Amiodarone-induced thyroid dysfunction: a clinical update

MN Elnaggar, K Jbeili, N Nik-Hussin… - Experimental and …, 2018 - thieme-connect.com
Amiodarone is one of the most commonly prescribed antiarrhythmic agents in clinical
practice owing to its efficacy, even with high toxicity profile. The high iodine content and the …

Amiodarone-induced thyroid dysfunction

S Danzi, I Klein - Journal of intensive care medicine, 2015 - journals.sagepub.com
Amiodarone is an effective medication for the treatment of cardiac arrhythmias. Originally
developed for the treatment of angina, it is now the most frequently prescribed …