Valsartan improves the electrophysiological characteristics of left ventricular hypertrophic myocardium in spontaneously hypertensive rats

H Zhi-Bin, F Chang, L Mao-Huan, Y Gui-Yi… - Hypertension …, 2014 - nature.com
The objective was to investigate the effects of valsartan on the electrophysiological
characteristics of left ventricular hypertrophic myocardium in spontaneously hypertensive …

The effect of valsartan on left ventricular myocardial functions in hypertensive patients with left ventricular hypertrophy

N Kucukler, IH Kurt, C Topaloglu… - Journal of …, 2012 - journals.lww.com
Background It has been shown by various diagnostic methodologies that angiotensin
receptor blockage reduces left ventricular mass, improves diastolic function and increases …

Sacubitril/valsartan reverses cardiac structure and function in experimental model of hypertension-induced hypertrophic cardiomyopathy

J Jeremic, N Govoruskina, J Bradic… - Molecular and Cellular …, 2023 - Springer
This study evaluated the effect of sacubtril/valsartan on cardiac remodeling, molecular and
cellular adaptations in experimental (rat) model of hypertension-induced hypertrophic …

Role of valsartan on myocardial Calpain I, calcineurin and Ca/calmodulin-dependent protein kinase IIδ expression of renovascular hypertensive rats

JY Lu, JH Zhu, XT Qin, XH Yu… - … xin xue Guan Bing za zhi, 2012 - europepmc.org
Objective To determine the protein expression of Calpain I, mRNA and protein expressions
and activity of calcineurin, and the alternative splicing of Ca/calmodulin-dependent protein …

Effects of physical exercise combined with captopril or losartan on left ventricular hypertrophy of hypertensive rats

QJ Tomaz de Castro, CM Araujo, PY Watai… - Clinical and …, 2021 - Taylor & Francis
Background: Left ventricular hypertrophy (LVH) is an endpoint of hypertensive cardiac
alterations. Renin-angiotensin-aldosterone system (RAAS) blockers are among the most …

Long‑term treatment of spontaneously hypertensive rats with losartan and molecular basis of modulating Ito of ventricular myocytes

H Zhang, S Wu, C Huang, X Li - Molecular Medicine …, 2014 - spandidos-publications.com
The present study aimed to determine the effect of chronic treatment with losartan on
transient outward potassium current (Ito) and the expression levels of potassium voltage …

Effect of combination of valsartan with benazepril on blood pressure and left ventricular hypertrophy in spontaneously hypertensive rats

KE Yong-Sheng, CAO Heng, Y Ting - Zhongguo yao li xue bao …, 2000 - europepmc.org
AIM: To evaluate the antihypertensive efficacy of angiotensin converting enzyme inhibitor
(ACEI) benazepril in combination with AT1 receptor antagonist valsartan and their effect on …

Effects of low-dose sacubitril/valsartan on different stages of cardiac hypertrophy in salt-loaded hypertensive rats

G Hamano, K Yamamoto, Y Takami… - Journal of …, 2019 - journals.lww.com
Background: Sacubitril/valsartan was shown to attenuate the development of cardiac
hypertrophy with enhanced blood pressure reduction compared with valsartan alone in …

Olmesartan improves left ventricular function in pressure-overload hypertrophied rat heart by blocking angiotensin II receptor with synergic effects of upregulation of …

K Ji, M Minakawa, K Fukui, Y Suzuki… - Therapeutic …, 2009 - journals.sagepub.com
It is not clear how the blocking effect of angiotensin II receptors by olmesartan affects the
functional recovery of pressure-overload hypertrophied heart. Hypertrophied heart was …

[PDF][PDF] Olmesartan medoxomil reverses left ventricle hypertrophy and reduces inflammatory cytokine IL-6 in the renovascular hypertensive rats

ZC Li, HY Yu, XX Wang, M Zhang… - Eur. Rev. Med …, 2013 - europeanreview.org
Olmesartan Medoxomil (OM) on left ventricle hypertrophy (LVH) and inflammatory cytokines
IL-6 and IL-10 levels in renovascular hypertensive rats. MATERIALS AND METHODS …