The underestimated role of the microphthalmia-associated transcription factor (MiTF) in normal and pathological haematopoiesis

A Oppezzo, F Rosselli - Cell & Bioscience, 2021 - Springer
Haematopoiesis, the process by which a restrained population of stem cells terminally
differentiates into specific types of blood cells, depends on the tightly regulated …

Emerging roles of MITF as a crucial regulator of immunity

A Lee, J Lim, JS Lim - Experimental & Molecular Medicine, 2024 - nature.com
Microphthalmia-associated transcription factor (MITF), a basic helix-loop-helix leucine zipper
transcription factor (bHLH-Zip), has been identified as a melanocyte-specific transcription …

Mitf-D, a newly identified isoform, expressed in the retinal pigment epithelium and monocyte-lineage cells affected by Mitf mutations

K Takeda, K Yasumoto, N Kawaguchi, T Udono… - … et Biophysica Acta (BBA …, 2002 - Elsevier
Microphthalmia-associated transcription factor (Mitf) regulates the differentiation of
melanocytes, optic cup-derived retinal pigment epithelium (RPE), and some types of bone …

Melanocytes and the Microphthalmia Transcription Factor Network

E Steingrímsson, NG Copeland, NA Jenkins - Annu. Rev. Genet., 2004 - annualreviews.org
▪ Abstract The first mouse microphthalmia transcription factor (Mitf) mutation was discovered
over 60 years ago, and since then over 24 spontaneous and induced mutations have been …

MITF: master regulator of melanocyte development and melanoma oncogene

C Levy, M Khaled, DE Fisher - Trends in molecular medicine, 2006 - cell.com
Microphthalmia-associated transcription factor (MITF) acts as a master regulator of
melanocyte development, function and survival by modulating various differentiation and …

Fifteen‐year quest for microphthalmia‐associated transcription factor target genes

Y Cheli, M Ohanna, R Ballotti… - Pigment cell & …, 2010 - Wiley Online Library
Microphthalmia‐associated transcription factor (MITF) was initially shown to play a key role
in melanocyte differentiation through the direct transcriptional control of TYROSINASE …

[HTML][HTML] The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology

A Kawakami, DE Fisher - Laboratory investigation, 2017 - Elsevier
Certain transcription factors have vital roles in lineage development, including specification
of cell types and control of differentiation. Microphthalmia-associated transcription factor …

MITF: A Matter of Life and Death for Developing Melanocytes

H Arnheiter, L Hou, MTT Nguyen, K Bismuth… - From Melanocytes to …, 2006 - Springer
Since its discovery over a decade ago, the microphthalmia-associated transcription factor
(MITF), has moved ever more to the center of pigment cell biology. Not only has MITF been …

[HTML][HTML] MITF-M, a “melanocyte-specific” isoform, is expressed in the adult retinal pigment epithelium

J Maruotti, T Thein, DJ Zack, N Esumi - Pigment cell & melanoma …, 2012 - ncbi.nlm.nih.gov
The gene residing at the microphthalmia locus that causes white and small eye phenotype
in mice when mutated was cloned and named microphthalmia-associated transcription …

A big gene linked to small eyes encodes multiple Mitf isoforms: many promoters make light work

KENI YASUMOTO, S Amae, T Udono… - Pigment cell …, 1998 - Wiley Online Library
Among more than 80 different loci related to mouse coat color, microphthalmia‐associated
transcription factor (Mitf) encoded at the mouse microphthalmia locus is one of the most …