Given the limited access to clinical material for studying the pathogenesis of Parkinson's
disease (PD), these studies should be carried out on experimental models. We have …

Dopamine was first synthesized in 1910. It was initially named 3-hydroxytyramine and
gained little interest in the science community. About a half-century later, neuroscientists …

Parkinson's disease (PD) often displays a strong unilateral predominance in arising
symptoms. PD is correlated with dopamine neuron (DAN) degeneration in the substantia …

The review of Lindholm et al.[1] is very interesting and raised a very important point which
require a more deeply discussion. This publication reveals the failure of both the scientific …

Dopaminergic neurons in the mammalian brain have received substantial attention in the
past given their fundamental role in several body functions and behaviours. The largest …

The mechanism of nigral dopaminergic neuronal degeneration in Parkinson's disease (PD)
is unknown. One of the pathological characteristics of the disease is the deposition of α …

We have recently shown that the periventricular nucleus (PeVN) of adult rats is a “mixed
dopaminergic (DAergic) center” containing three thousand neurons: DAergic neurons and …

Dopamine controls various physiological functions in the brain and periphery by acting on its
receptors D1, D2, D3, D4, and D5. Dopamine receptors are G protein–coupled receptors …

Understanding the development of neuronal systems has become an important asset in the
attempt to solve complex questions about neuropathology as found in Parkinson's disease …

To visualize and isolate live dopamine (DA)-producing neurons in the embryonic ventral
mesencephalon, we generated transgenic mice expressing green fluorescent protein (GFP) …