This study was aimed to test our hypothesis about dopamine (DA) synthesis by non-DAergic
neurons expressing individual complementary enzymes of the DA synthetic pathway in …

To visualize and isolate live dopamine (DA)-producing neurons in the embryonic ventral
mesencephalon, we generated transgenic mice expressing green fluorescent protein (GFP) …

Parkinson's disease (PD) is, to a large extent, specific to the human species. Most symptoms
are the consequence of the preferential degeneration of the dopamine‐synthesizing cells of …

Since the late 80s it has been repeatedly shown that besides dopaminergic neurons, the
brain contains so-called monoenzymatic neurons possessing one of the enzymes of …

Parkinson's disease (PD) is a progressive neurodegenerative disease, which causes a
tremendous socioeconomic burden. PD patients are suffering from debilitating motor and …

Although loss of midbrain dopaminergic neurons is associated with one of the most common
human neurological disorders, Parkinson's disease, little is known about the specification of …

Parkinson's disease is caused by a progressive loss of the midbrain dopamine (DA) neurons
in the substantia nigra pars compacta. Although the main cause of Parkinson's disease …

The irreversible loss of the dopamine-mediated control of striatal function is considered the
functional substrate of the motor symptoms of Parkinson's disease. This pathological event …

Parkinson's disease is a neurodegenerative disorder accompanied by depletion of
dopamine and loss of dopaminergic neurons in the brain that is believed to be responsible …

Nigrostriatal dopamine depletion disrupts striatal medium spiny neuron morphology in
Parkinson's disease and modulates striatal synaptic plasticity in animal models of …