Activation of cardiac STAT3 by IL-6 cytokine family contributes to cardioprotection.
Previously, we demonstrated that IL-11, an IL-6 cytokine family, has the therapeutic potential …

BACKGROUND Interleukin (IL)‐22, a member of the IL‐10 cytokine family, is the only known
cytokine that is secreted by immune cells but does not target immune cells; it mainly targets …

Recent research has shown that reparative (alternatively activated or M2) macrophages play
a role in repair of damaged tissues, including the infarcted hearts. Administration of IL-4 is …

Myocardial ischemia‐reperfusion injury (MIRI) is common clinical complication, which
represents significant challenge in the treatment of acute myocardial infarction (AMI) …

Objective: We sought to determine whether interleukin (IL)-6 modulates myocardial
infarction or the late phase of preconditioning (PC). Methods: Wild-type and IL-6−/− mice …

BACKGROUND: Cardiac surgery induces the release of inflammatory mediators that can
prolong cardiac dysfunction after operative intervention. Interleukin-10 (IL-10), a potent …

Background—Glycoprotein 130 is the common receptor subunit for the interleukin (IL)-6
cytokine family. Previously, we reported that pretreatment of IL-11, an IL-6 family cytokine …

Myocardial ischemia reperfusion (I/R) injury is a complex process with intense inflammatory
response and cardiomyocyte apoptosis. As a decoy receptor of IL-1β, Interleukin-1 receptor …

Abstract Interleukin (IL)‐7 is known to enhance the macrophages cytotoxic activity and that
macrophages play a pivotal role in the development and progression of myocardial …

Interleukin (IL)-6 family cytokines, which share glycoprotein 130 (gp130) as a signal-
transducing receptor component, play important roles in the maintenance of cardiac …