Dendritic cell vaccines for cancer therapy: fundamentals and clinical trials

GG Romagnoli, R Kaneno - … Bench to Bedside Immunotherapy of Cancers, 2021 - Springer
Since conventional chemo-and radiotherapy and surgery are not completely satisfactory to
fight cancer, active and passive immunotherapeutic approaches have figured as effective …

Dendritic cell vaccines for cancer therapy

GM Sprinzl, L Kacani… - Cancer …, 2001 - cancertreatmentreviews.com
Dendritic cells (DC) are professional antigen-presenting cells whose primary function is the
initiation of immune response. Based on the finding that the immune system usually fails to …

[HTML][HTML] Advances in dendritic cell vaccination therapy of cancer

S Najafi, K Mortezaee - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Traditionally, vaccines have helped eradication of several infectious diseases and also
saved millions of lives in the human history. Those prophylactic vaccines have acted through …

Dendritic cells in anticancer vaccination: rationale for ex vivo loading or in vivo targeting

AV Baldin, LV Savvateeva, AV Bazhin, AA Zamyatnin Jr - Cancers, 2020 - mdpi.com
Dendritic cells (DCs) have shown great potential as a component or target in the landscape
of cancer immunotherapy. Different in vivo and ex vivo strategies of DC vaccine generation …

[PDF][PDF] Dendritic cell-based vaccines in cancer immunotherapy: an update on clinical and immunological results.

WJ Lesterhuis, IJM de Vries, GJ Adema, CJA Punt - 2004 - repository.ubn.ru.nl
The immunogenicity of tumors has been established. Aspecific stimulation of immunity, such
as by cytokine therapy, has been shown to induce durable clinical remissions in metastatic …

Dendritic cell–based immunotherapy: state of the art and beyond

KF Bol, G Schreibelt, WR Gerritsen, IJM De Vries… - Clinical cancer …, 2016 - AACR
Dendritic cell (DC) vaccination in cancer patients aims to induce or augment an effective
antitumor immune response against tumor antigens and was first explored in a clinical trial …

Novel dendritic cell vaccine strategies

PV Munson, LH Butterfield, J Adamik - Cancer vaccines as immunotherapy …, 2022 - Elsevier
Dendritic cells (DCs) are a class of mostly myeloid lineage cells that are the key antigen-
presenting cells to both initiate and boost immune responses. Cancer vaccines based on …

Dendritic cell-based vaccine research against cancer

N Mody, S Dubey, R Sharma, U Agrawal… - Expert review of clinical …, 2015 - Taylor & Francis
Therapeutic vaccines that treat cancers with the help of the patient's own immune system
signify a feasible option for active immunotherapy against the disease. Dendritic cells (DCs) …

Dendritic-cell-based therapeutic vaccination against cancer

FO Nestle, A Farkas, C Conrad - Current opinion in immunology, 2005 - Elsevier
Early clinical trials, in which over 1000 cancer patients received dendritic cell (DC) vaccines,
tested different vaccine preparations, but they did not always induce sufficient acquired …

Therapeutic Dendritic Cell− Based Cancer Vaccines: The State of the Art

MM Strioga, T Felzmann, DJ Powell Jr… - Critical Reviews™ in …, 2013 - dl.begellhouse.com
Dendritic cells (DCs) are the most potent professional antigen-presenting cells, capable of
initiating proper adaptive immune responses. Although tumor-infiltrating DCs are able to …