The use of dendritic cells in cancer immunotherapy

A Nencioni, F Grünebach, SM Schmidt… - Critical reviews in …, 2008 - Elsevier
Cancer immunotherapy aims at eliciting an immune response directed against tumor
antigens to help fight off residual tumor cells and thereby improve survival and quality of life …

[HTML][HTML] Dendritic cell-based therapeutic cancer vaccines: past, present and future

MS Ahmed, YS Bae - Clinical and experimental vaccine …, 2014 - synapse.koreamed.org
Md. Selim Ahmed et al• Dendritic cell-based tumor vaccine 114 http://www. ecevr. org/
http://dx. doi. org/10.7774/cevr. 2014.3. 2.113 of 7.1%[4]. Though not firmly established, the …

Potentiation strategies of dendritic cell-based antitumor vaccines: combinational therapy takes the front seat

M Torabi-Rahvar, M Bozorgmehr, M Jeddi-Tehrani… - Drug discovery today, 2011 - Elsevier
Despite recent attempts to take advantage of dendritic cell (DC)-based vaccines for cancer
immunotherapy, the results of clinical studies have been disappointing. This is mainly as a …

[HTML][HTML] Does the immunocompetent status of cancer patients have an impact on therapeutic DC vaccination strategies?

S Martin Lluesma, M Graciotti, CLL Chiang… - Vaccines, 2018 - mdpi.com
Although different types of therapeutic vaccines against established cancerous lesions in
various indications have been developed since the 1990s, their clinical benefit is still very …

Cancer vaccines for established cancer: how to make them better?

DM Andrews, E Maraskovsky… - Immunological reviews, 2008 - Wiley Online Library
If one envisions dendritic cells (DCs) as nature's adjuvant, then it is easy to predict that they
would be advantageous for cancer immunotherapy. Advances in culture processes that …

Clinical application of dendritic cells in cancer vaccination therapy

IM Svane, ML Soot, S Buus, HE Johnsen - Apmis, 2003 - Wiley Online Library
During the last decade use of dendritic cells (DC) has moved from murine and in vitro
studies to clinical trials as adjuvant in cancer immunotherapy. Here they function as delivery …

Dendritic cell-based vaccines and therapies for cancer

T Tatsumi, WJ Storkus - Expert Opinion on Biological Therapy, 2002 - Taylor & Francis
Dendritic cells (DCs) are the most potent professional antigen-presenting cells (APCs), and
are capable of stimulating naive T cells and driving primary immune responses. Due to this …

Clinical trials of dendritic cell-based cancer vaccines in hematologic malignancies

AR Pyzer, DE Avigan, J Rosenblatt - Human vaccines & …, 2014 - Taylor & Francis
The potential for the immune system to target hematological malignancies is demonstrated
in the allogeneic transplant setting, where durable responses can be achieved. However …

Dendritic cell-based vaccines: from mouse models to clinical cancer immunotherapy

MWJ Schreurs, AAO Eggert, CJA Punt… - Critical Reviews™ in …, 2000 - dl.begellhouse.com
ABSTRACT B and T lymphocytes are the effectors of specific immunity. However, their
function is critically dependent on dendritic cells (DC). DC are professional antigen …

Dendritic cell-based vaccination against cancer

G Schuler - Cancer Immunity, 2003 - AACR
Among the many cancer therapeutics being presently developed, antigen-specific
immunotherapy is considered a particularly promising approach. Active immunotherapy or …