Luteolysis in ruminants: past concepts, new insights, and persisting challenges

R Meidan, E Girsh, R Mamluk, N Levy… - The Life Cycle of the …, 2017 - Springer
It is well established that in ruminants, and in other species with estrous cycles, luteal
regression is stimulated by the episodic release of prostaglandin F2α (PGF2α) from the …

Growth and regression in bovine corpora lutea: regulation by local survival and death pathways

DJ Skarzynski, KK Piotrowska‐Tomala… - … in Domestic Animals, 2013 - Wiley Online Library
Contents The bovine corpus luteum (CL) is a transient gland with a life span of only 18 days
in the cyclic cow. Mechanisms controlling CL development and secretory function may …

[HTML][HTML] Luteal prostaglandins: mechanisms regulating luteal survival and demise in ruminants

JL Pate, CHK Hughes - animal, 2023 - Elsevier
The corpus luteum (CL) is critical for establishment and maintenance of pregnancy in all
mammals. However, the fate of the CL in ruminants is dependent on the presence of a …

Life or death decisions in the corpus luteum

JL Pate, CJ Johnson‐Larson… - … in Domestic Animals, 2012 - Wiley Online Library
Contents The corpus luteum (CL) is an ephemeral endocrine organ. During its lifespan, it
undergoes a period of extremely rapid growth that involves hypertrophy, proliferation and …

Corpus luteum regression and early pregnancy maintenance in pigs

AJ Ziecik, E Przygrodzka, MM Kaczmarek - The life cycle of the corpus …, 2017 - Springer
Abstract Development of the porcine corpus luteum (CL) requires the initial preovulatory LH
surge and support of many biologically active agents including tonic secretion of LH, ovarian …

Luteolysis and the Corpus Luteum of pregnancy

CK Hughes, JL Pate - The Ovary, 2019 - Elsevier
The corpus luteum (CL) is a transient endocrine gland that produces progesterone and
maintains pregnancy in all mammals. In the absence of a pregnancy, the CL regresses …

Loss of luteal sensitivity to luteinizing hormone underlies luteolysis in cattle: A hypothesis

HK Shrestha - Reproductive Biology, 2021 - Elsevier
By virtue of the secretion of progesterone (P4), corpus luteum (CL) is important not only for
normal cyclicity but also for conception and continuation of pregnancy in female mammals …

[HTML][HTML] Regulation of the porcine corpus luteum during pregnancy

AJ Ziecik, E Przygrodzka, BM Jalali… - …, 2018 - rep.bioscientifica.com
The new corpora lutea (CLs) in pigs are formed from the preovulatory follicles after the
luteinizing hormone (LH) surge. However, total autonomy and independence of CLs from LH …

Sensitivity of Bovine Corpora Lutea to Prostaglandin F Is Dependent on Progesterone, Oxytocin, and Prostaglandins

DJ Skarzynski, K Okuda - Biology of reproduction, 1999 - academic.oup.com
Prostaglandin (PG) F2α that is released from the uterus is essential for spontaneous
luteolysis in cattle. Although PGF2α and its analogues are extensively used to synchronize …

Regulation of progesterone and prostaglandin F2α production in the CL

FJ Diaz, LE Anderson, YL Wu, A Rabot, SJ Tsai… - Molecular and cellular …, 2002 - Elsevier
After the luteinizing hormone (LH) surge, the cells that remain from the ovulated follicle
undergo a process of differentiation termed luteinization. Two key features of the cells after …