Effects of hydroxysafflor yellow A in the attenuation of MPTP neurotoxicity in mice

B Han, H Zhao - Neurochemical research, 2010 - Springer
Parkinson's disease (PD) is a progressive neurodegenerative disorder whose etiology is not
understood. The 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-treated mouse …

Neuroprotective effect of hydroxysafflor yellow A on 6-hydroxydopamine-induced Parkinson's disease in rats

B Han, J Hu, J Shen, Y Gao, Y Lu, T Wang - European journal of …, 2013 - Elsevier
Parkinson's disease (PD) is a progressive neurodegenerative disorder affecting
predominantly the dopaminergic mesotelencephalic system. Enormous progress has been …

Fucoxanthin attenuates behavior deficits and neuroinflammatory response in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced Parkinson's disease in mice

G Sun, T Xin, R Zhang, C Liu, Q Pang - Pharmacognosy Magazine, 2020 - phcog.com
Background: Parkinson's disease (PD) is one of the foremost neurological disorders which is
differentiated next to the progressive dopamine (DA) loss, especially in the area of …

Neuroprotective and Neurorestorative Effects of Holothuria scabra Extract in the MPTP/MPP+-Induced Mouse and Cellular Models of Parkinson's Disease

K Noonong, P Sobhon, M Sroyraya… - Frontiers in …, 2020 - frontiersin.org
Extracts from Holothuria scabra (HS) have been shown to possess anti-inflammation, anti-
oxidant and anti-cancer activities. More recently, it was shown to have neuroprotective …

Protective effect of hydroxysafflor yellow A on dopaminergic neurons against 6-hydroxydopamine, activating anti-apoptotic and anti-neuroinflammatory pathways

X Yang, Y Li, L Chen, M Xu, J Wu, P Zhang… - Pharmaceutical …, 2020 - Taylor & Francis
Abstract Context Hydroxysafflor yellow A (HSYA) has been shown to have neuroprotective
effects in cerebral infarction. However, its underlying roles in apoptosis and inflammation in …

Neuroprotective effect of arundic acid, an astrocyte-modulating agent, in mouse brain against MPTP (1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine) neurotoxicity

T Himeda, N Kadoguchi, Y Kamiyama, H Kato… - …, 2006 - Elsevier
1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) causes the damage of dopaminergic
neurons as seen in Parkinson's disease. Oxidative stress has been as one of several …

Neuroprotective Effects of San‐Huang‐Xie‐Xin‐Tang in the MPP+/MPTP Models of Parkinson's Disease In Vitro and In Vivo

YC Lo, YT Shih, YT Tseng… - … Based Complementary and …, 2012 - Wiley Online Library
San‐Huang‐Xie‐Xin‐Tang (SHXT), composed of Coptidis rhizoma, Scutellariae radix, and
Rhei rhizoma, is a traditional Chinese medicine used for complementary and alternative …

Asiaticoside, a trisaccaride triterpene induces biochemical and molecular variations in brain of mice with parkinsonism

U Sampath, VA Janardhanam - Translational Neurodegeneration, 2013 - Springer
Background Parkinson's disease characterized by oxidative stress and mitochondrial
damage in the pars compacta of substantia nigra remains a challenge to manage with an …

Protective effect of a novel herbmedicine, Hepad, on apoptosis of SH-SY5Y cells and a rat model of Parkinson's disease

SY Baek, NR Lee, DH Kim, A Gu, SY Kim… - Molecular & Cellular …, 2015 - Springer
Parkinson's disease (PD) is a neurodegenerative disorder characterized by loss of
dopaminergic neurons in the substantia nigra pars compacta. In this study, we investigated …

Phloretin attenuates behavior deficits and neuroinflammatory response in MPTP induced Parkinson's disease in mice

G Zhang, G Yang, J Liu - Life sciences, 2019 - Elsevier
Neuroinflammation is one of the significant neuropathological conditions in Parkinson's
disease (PD) which is due to microglial and astrocytes activation leads to progressive …