Development of finasteride/PHBV@ polyvinyl alcohol/chitosan reservoir-type microspheres as a potential embolic agent: from in vitro evaluation to animal study

X Li, X Ji, K Chen, MW Ullah, X Yuan, Z Lei… - Biomaterials …, 2020 - pubs.rsc.org
Benign prostatic hyperplasia (BPH) is a prevalent urological disease affecting elders.
Currently, the prostatic artery embolization (PAE) is considered as a minimally invasive and …

Microencapsulation of poorly water-soluble finasteride in polyvinyl alcohol/chitosan microspheres as a long-term sustained release system for potential embolization …

X Li, K Chen, X Ji, X Yuan, Z Lei, MW Ullah… - Engineered …, 2020 - espublisher.com
Prostatic artery embolization (PAE) has been widely applied as an alternative option to treat
symptomatic benign prostatic hyperplasia (BPH). However, hitherto, very few drug-loaded …

Water-stable and finasteride-loaded polyvinyl alcohol nanofibrous particles with sustained drug release for improved prostatic artery embolization—In vitro and in vivo …

X Li, B Li, MW Ullah, R Panday, J Cao, Q Li… - Materials Science and …, 2020 - Elsevier
Prostatic artery embolization (PAE) has been a well-established treatment for benign
prostatic hyperplasia (BPH). To enhance the therapeutic efficacy, a strategy is to use …

[HTML][HTML] Immobilized thrombin on X-ray radiopaque polyvinyl alcohol/chitosan embolic microspheres for precise localization and topical blood coagulation

X Li, X Ji, K Chen, MW Ullah, B Li, J Cao, L Xiao… - Bioactive Materials, 2021 - Elsevier
Trans-catheter arterial embolization (TAE) plays an important role in treating various
diseases. The available embolic agents lack X-ray visibility and do not prevent the reflux …

In vitro and in vivo evaluation of biodegradable embolic microspheres with tunable anticancer drug release

L Weng, P Rostamzadeh, N Nooryshokry, HC Le… - Acta biomaterialia, 2013 - Elsevier
Natural polymer-derived materials have attracted increasing interest in the biomedical field.
Polysaccharides have obvious advantages over other polymers employed for biomedical …

A novel embolic microspheres with micro nano binary progressive structure for transarterial chemoembolization applications

L Wei-Ze, H Wen-Xia, Z Ning, H Shu-Miao, L Fei… - European Journal of …, 2020 - Elsevier
In this work, a novel embolic microspheres with micro nano binary progressive structure (MN-
Ms) were developed for transarterial chemoembolization (TCE) applications. The Bletilla …

Hyaluronic acid-based nano-sized drug carrier-containing Gellan gum microspheres as potential multifunctional embolic agent

MF Hsu, YS Tyan, YC Chien, MW Lee - Scientific Reports, 2018 - nature.com
The purpose of this study was to develop a gellan gum-based multifunctional embolic agent.
Calibrated spherical gellan gum and nanoparticle-containing gellan gum microspheres …

Development of PVA-based microsphere as a potential embolization agent

X Yang, S Wang, X Zhang, C Ye, S Wang, X An - Biomaterials Advances, 2022 - Elsevier
The development of tissue adhesive embolization microspheres with imaging ability is one
of the important methods to improve the efficacy of interventional embolization. This study …

Synthesis and assessment of drug-eluting microspheres for transcatheter arterial chemoembolization

L Du, Y Huang, Q Zhang, Y Zhou, J Huang, L Yan… - Acta Biomaterialia, 2019 - Elsevier
Transcatheter arterial chemoembolization (TACE) is well known as an effective treatment for
inoperable hepatocellular carcinoma (HCC). In this study, a novel embolic agent of ion …

Preparation and evaluation of ion-exchange porous polyvinyl alcohol microspheres as a potential drug delivery embolization system

X Li, X Ji, K Chen, X Yuan, Z Lei, MW Ullah… - Materials Science and …, 2021 - Elsevier
The present study aimed to develop a new drug delivery system with efficient drug loading
and sustained drug release for potential application in transarterial chemoembolization …