Introduction Associations between cerebral small vessel disease (SVD) and inflammation
have been largely examined using peripheral blood markers of inflammation, with few …

Inflammation is increasingly implicated as a risk factor for dementia, stroke, and small vessel
disease (SVD). However, the underlying mechanisms and causative pathways remain …

Importance It remains unclear if and how associations between cerebral small-vessel
disease and Alzheimer disease (AD) pathology lead to cognitive decline and dementia …

Neuropsychiatric symptoms (NPS) affect the quality of life of patients with dementia and
increase the burden on caregivers. We aimed to evaluate how small vessel disease (SVD) …

Background and Objectives Small vessel disease (SVD) and neuroinflammation both occur
in Alzheimer disease (AD) and other neurodegenerative diseases. It is unclear whether …

Background Markers of cerebrovascular disease are common in dementia, and may be
present before dementia onset. However, their clinical relevance in midlife adults at risk of …

Background This study investigated the relationships of neutrophil count (NC), neutrophil-to-
lymphocyte ratio (NLR) and systemic immune-inflammation index (SII) with cerebral small …

Importance Cerebrovascular disease (CVD) and Alzheimer disease are significant causes of
cognitive impairment in the elderly. However, few studies have evaluated the relationship …

Background and purpose Although inflammation has been proposed to be a candidate risk
factor for cerebral small vessel disease (CSVD), previous findings remain largely …

Background: Cerebral small vessel disease (SVD) and neuropsychiatric symptoms (NPS)
independently increase the risk of cognitive decline. While their co-existence has been …