A hypoxia-irrelevant Fe-doped multivalent manganese oxide sonosensitizer via a vacancy engineering strategy for enhanced sonodynamic therapy

L Sun, Y Cao, Z Lu, P Ding, Z Wang, F Ma, Z Wang… - Nano Today, 2022 - Elsevier
Sonodynamic therapy (SDT), as a noninvasive treatment with preferable therapeutic depth,
has attracted widespread attention. However, current sonosensitizers suffer from a low …

Ultrathin‐FeOOH‐Coated MnO2 Sonosensitizers with Boosted Reactive Oxygen Species Yield and Remodeled Tumor Microenvironment for Efficient Cancer Therapy

Q Liu, L Shi, Y Liao, X Cao, X Liu, Y Yu… - Advanced …, 2022 - Wiley Online Library
Sonodynamic therapy (SDT) typically suffers from compromised anticancer efficacy owing to
the low reactive oxygen species (ROS) yield and complicated tumor microenvironment …

A New Sono‐Chemo Sensitizer Overcoming Tumor Hypoxia for Augmented Sono/Chemo‐Dynamic Therapy and Robust Immune‐Activating Response

L Sun, W Gao, J Wang, X Niu, N Kurniawan, L Li, ZP Xu - Small, 2023 - Wiley Online Library
Novel sonosensitizers with intrinsic characteristics for tumor diagnosis, efficient therapy, and
tumor microenvironment regulation are appealing in current sonodynamic therapy. Herein, a …

MOF‐derived double‐layer hollow nanoparticles with oxygen generation ability for multimodal imaging‐guided sonodynamic therapy

X Pan, W Wang, Z Huang, S Liu, J Guo… - Angewandte …, 2020 - Wiley Online Library
The high reactive oxygen species (ROS) generation ability and simple construction of
sonosensitizer systems remain challenging in sonodynamic therapy against the hypoxic …

Photosynthetic Oxygenation‐Augmented Sonodynamic Nanotherapy of Hypoxic Tumors

S Lu, W Feng, C Dong, X Song, X Gao… - Advanced …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) has been employed as a powerful therapeutic agent for
eradicating tumor via oxidative stress. As an emerging ROS‐involving noninvasive …

Metal–Organic Framework (MOF)‐Based Ultrasound‐Responsive Dual‐Sonosensitizer Nanoplatform for Hypoxic Cancer Therapy

C Zhang, L Xin, J Li, J Cao, Y Sun… - Advanced …, 2022 - Wiley Online Library
Sonodynamic therapy (SDT), which uses reactive oxygen species to target tumors, has
shown promise in the management of unresectable cancers. However, the hypoxic tumor …

Ultrasmall Oxygen‐Deficient Bimetallic Oxide MnWOX Nanoparticles for Depletion of Endogenous GSH and Enhanced Sonodynamic Cancer Therapy

F Gong, L Cheng, N Yang, O Betzer, L Feng… - Advanced …, 2019 - Wiley Online Library
Sonodynamic therapy (SDT) triggered by ultrasound (US) has attracted increasing attention
owing to its abilities to overcome critical limitations including low tissue‐penetration depth …

[HTML][HTML] Engineering Fe/Mn-doped zinc oxide nanosonosensitizers for ultrasound-activated and multiple ferroptosis-augmented nanodynamic tumor suppression

Z Hu, X Song, L Ding, Y Cai, L Yu, L Zhang, Y Zhou… - Materials Today Bio, 2022 - Elsevier
As an effective tumor-therapeutic modality, ultrasound-triggered sonodynamic therapy (SDT)
has been extensively explored to induce cancer cell death by activating sonosensitizers to …

An ultrasound-triggered nanoplatform for synergistic sonodynamic-nitric oxide therapy

L Wang, Y Tian, K Lai, Y Liu, Y Liu, J Mou… - ACS Biomaterials …, 2023 - ACS Publications
Ultrasound (US)-triggered sonodynamic therapy (SDT) has aroused intensive interest as a
powerful alternative for cancer treatment in recent years due to its non-invasiveness and …

A hypoxia responsive nanoassembly for tumor specific oxygenation and enhanced sonodynamic therapy

K Yang, L Yue, G Yu, L Rao, R Tian, J Wei, Z Yang… - Biomaterials, 2021 - Elsevier
The hypoxic tumor microenvironment (TME) and non-specific distribution of sonosensitizers
are two major obstacles that limit practical applications of sonodynamic therapy (SDT) in …