Asthma is a chronic disease, affecting approximately 350 million people worldwide.
Inflammation and remodeling in asthma involve the large airways, and it is now widely …

Introduction Small airway disease (SAD) represents a common and critical feature of
Chronic Obstructive Pulmonary Disease (COPD). Introduced in the'60s, SAD has gradually …

Background Small airways dysfunction (SAD) is well recognised in asthma, yet its role in the
severity and control of asthma is unclear. This study aimed to assess which combination of …

An estimated 300 million people suffer from asthma worldwide, which is a major public
health problem [1]. Asthma is a chronic inflammatory lung disease that affects the entire …

Evidence that enables us to identify, assess, and access the small airways in asthma and
chronic obstructive pulmonary disease (COPD) has led INTERASMA (Global Asthma …

Identification of pathologic changes in early and mild obstructive lung disease has shown
the importance of the small airways and their contribution to symptoms. Indeed, significant …

Background Although small airway disease is a feature of asthma, its association with
relevant asthma outcomes remains unclear. The ATLANTIS study was designed to identify …

Asthma and COPD have a high personal, societal, and economic impact. Both diseases are
characterized by airway obstruction and an inflammatory process. The inflammatory process …

COPD and asthma have different risk factors and pathogenesis, but they share a
pathophysiologic hallmark characterized by small airways disease. Although difficult to …

The small airways have been neglected for many years, but interest in the topic has been
rekindled with recent advances in measurement techniques to assess this region and also …