Are there animal models of IgA nephropathy?

RC Monteiro, Y Suzuki - Seminars in Immunopathology, 2021 - Springer
Abstract Immunoglobulin A (IgA) nephropathy (IgAN) is the most common primary
glomerulonephritis worldwide. Up to 40% of IgAN patients develop end-stage kidney …

History of IgA nephropathy mouse models

B Wehbi, V Pascal, L Zawil, M Cogné… - Journal of Clinical …, 2021 - mdpi.com
IgA nephropathy (IgAN) is the most common primary glomerulonephritis in the world. It was
first described in 1968 by Jean Berger and Nicole Hinglais as the presence of intercapillary …

Murine models of human IgA nephropathy

H Suzuki, Y Suzuki - Seminars in Nephrology, 2018 - Elsevier
IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis in the world.
IgAN is characterized by mesangial deposits of IgA1-containing immune complexes. IgA1 …

New insights into the pathogenesis of IgA nephropathy

J Floege, IC Moura, MR Daha - Seminars in immunopathology, 2014 - Springer
IgA nephropathy (IgAN) is the most common diagnosis amongst primary glomerular
diseases in most countries where renal biopsies are regularly performed. Only a fraction of …

Immunological drivers of IgA nephropathy: Exploring the mucosa–kidney link

H Selvaskandan, J Barratt… - International Journal of …, 2022 - Wiley Online Library
IgA nephropathy (IgAN) is the most common pattern of primary glomerular disease reported
worldwide. Up to 40% of those with IgAN progress to end‐stage kidney disease within 20 …

Development of animal models of human IgA nephropathy

H Suzuki, Y Suzuki, J Novak, Y Tomino - Drug Discovery Today: Disease …, 2014 - Elsevier
IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis in the world.
IgAN is characterized by the mesangial accumulation of immune complexes containing …

Role of IgA receptors in the pathogenesis of IgA nephropathy

SM Lechner, C Papista, JM Chemouny, L Berthelot… - Journal of …, 2016 - Springer
Immunoglobulin A nephropathy (IgAN) or Berger's disease is the most common form of
primary glomerulonephritis in the world and one of the first causes of end-stage renal failure …

IgA nephropathy: an interesting autoimmune kidney disease

A Rajasekaran, BA Julian, DV Rizk - The American journal of the medical …, 2021 - Elsevier
Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide. It is a leading cause of chronic kidney disease and progresses to end-stage …

Present and future therapy options in IgA-nephropathy

J Floege, F Eitner - Journal of nephrology, 2005 - pubmed.ncbi.nlm.nih.gov
Over the last 5 years the evidence base for therapeutic approaches in patients at risk for
progressive IgA-nephropathy (IgAN) has markedly improved. In addition to several studies …

Immune abnormalities in IgA nephropathy

M Gentile, L Sanchez-Russo, LV Riella… - Clinical Kidney …, 2023 - academic.oup.com
ABSTRACT Immunoglobulin A (IgA) nephropathy (IgAN) is the most common primary
glomerulonephritis worldwide and it is characterized by mesangial IgA deposition …