Multiple sclerosis (MS) is a multicomponent disease that is marked by continual
inflammation, demyelination and irreparable damage to the central nervous system. While it …

Over the past two decades B cells have increasingly moved into the spotlight in multiple
sclerosis (MS) research. This interest was fuelled by growing understanding and acceptance …

Interest in the role of B-cells in multiple sclerosis (MS) pathogenesis has increased, and a
number of B-cell targeted therapies are currently in clinical trials. B-cells are key mediators …

Background: Collectively, research on the role of B-cells in the pathogenesis of multiple
sclerosis (MS) illustrates how translational medicine has given rise to promising therapeutic …

There is ongoing debate on how B cells contribute to the pathogenesis of multiple sclerosis
(MS). The success of B‐cell targeting therapies in MS highlighted the role of B cells …

Multiple sclerosis (MS) is a chronic disease of the central nervous system (CNS), in which
auto-aggressive lymphocytes participate in inflammation that causes myelin destruction …

Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system
with no clear etiology. Until recently, most studies have emphasized the role of T cells in the …

B lymphocytes have essential roles in the autoimmune pathogenesis of multiple sclerosis
(MS). They regulate the autoimmune response and participate in the development of the …

Increasing evidence indicates the involvement of B cells in the pathogenesis of multiple
sclerosis (MS), but their precise roles are unclear. In this Review, we provide an overview of …

There is growing recognition that B cell contributions to normal immune responses extend
well beyond their potential to become antibody-producing cells, including roles at the innate …