Objective To compare intravenous methylprednisolone (IVMP) with oral prednisolone (OP)
for the treatment of West syndrome. Methods In this randomized, open-label trial, children …

Objective To assess the feasibility, effectiveness, and safety of pulse methylprednisolone in
comparison with intramuscular adrenocorticotropic hormone (ACTH) therapy in children with …

Background This article explores the role of initial treatment on control of spasms and other
epilepsies at four years in children previously treated for West syndrome. Methods The Sri …

OBJECTIVE To review the current literature on the efficacy and safety of low-versus high-
dose adrenocorticotropic hormone (ACTH) regimens, low-dose ACTH regimens, and …

Summary Infantile Epileptic Spasms Syndrome (IESS), commonly known as West syndrome,
is the most common cause of infantile-onset epileptic encephalopathy. There is a peculiar …

To study the efficacy of adrenocorticotrophic hormone (ACTH) in treating Taiwanese
children with West syndrome (WS) and the impact on long-term prognosis, 66 patients with …

Objective Hormonal therapy and vigabatrin are now accepted as the first-line or standard
therapies for West syndrome (WS). However, the superiority of these drugs in terms of …

West syndrome (WS; we prefer this term instead of infantile spasms) is a catastrophic
devastating neurologic disorder preferentially affecting infants within a narrow age range. It …

We studied the effectiveness of our new ACTH treatment strategy for West syndrome (WS),
which was based on the results of our previous extremely low-dose ACTH study. The …

Objective The efficacy and adverse effects of conventional dose and low dose
adrenocorticotrophic hormone (ACTH) therapy for West syndrome (WS) were compared in …