Antiepileptic drug treatment of West syndrome

M Ito - Epilepsia, 1998 - Wiley Online Library
We sent questionnaires about current therapy for West syndrome (WS) to 208 institutions at
which the pediatric members of the Japan Epilepsy Society were in residence. One hundred …

Extremely low-dose ACTH therapy for West syndrome in Japan

M Ito - Brain and Development, 2001 - Elsevier
Adrenocorticotropic hormone (ACTH) therapy is a widely used and effective treatment for
West syndrome. However, serious adverse effects can occur during or shortly after ACTH …

A plausible explanation for superiority of adreno-cortico-trophic hormone (ACTH) over oral corticosteroids in management of infantile spasms (West syndrome)

H Jaseja - Medical hypotheses, 2006 - Elsevier
West syndrome (WS), an age dependent epileptic encephalopathy is identified as a triad of
infantile spasms (IS), psychomotor retardation and a specific EEG pattern known as …

Predictive factors for relapse of epileptic spasms after adrenocorticotropic hormone therapy in West syndrome

Y Hayashi, H Yoshinaga, T Akiyama, F Endoh… - Brain and …, 2016 - Elsevier
Purpose To investigate whether serial electroencephalographic (EEG) findings can predict
relapse of epileptic spasms after synthetic adrenocorticotropic hormone (ACTH) therapy in …

West syndrome: response to valproate

S Chandra, A Bhave, R Bhargava, C Kumar… - Frontiers in …, 2012 - frontiersin.org
Management of West syndrome is unsatisfactory. In our clinic we observed that a significant
proportion of patients respond to usual dose of valproate. Objective: To prospectively assess …

Efficacy of treatments for infantile spasms: a systematic review

JM Song, J Hahn, SH Kim… - Clinical …, 2017 - journals.lww.com
Objectives West syndrome (also known as infantile spasm because of its main seizure type)
is a rare form of epilepsy that begins during early infancy. Recent guidelines and reviews on …

Intravenous immunoglobulin therapy is rarely effective as the initial treatment in West syndrome: a retrospective study of 70 patients

R Matsuura, S Hamano, Y Hirata, A Oba… - Journal of the …, 2016 - Elsevier
Purpose To evaluate factors influencing the efficacy and safety of intravenous
immunoglobulins (IVIG) therapy for West syndrome. Methods We investigated seizure …

Long‐term mortality of patients with West syndrome

M Sillanpää, R Riikonen, MM Saarinen… - Epilepsia …, 2016 - Wiley Online Library
Objective To study long‐term survival and mortality among patients with West syndrome.
Methods The study population included all children born in 1960–1976 and treated for West …

Randomized, single-blind, parallel clinical trial on efficacy of oral prednisolone versus intramuscular corticotropin on immediate and continued spasm control in west …

J Wanigasinghe, C Arambepola, SS Ranganathan… - Pediatric …, 2015 - Elsevier
Objective A single-center, single-blind, parallel-group, randomized clinical trial was
performed to test the null hypothesis that adrenocorticotropic hormone is not superior to high …

What are the reasons for the strikingly different approaches to the use of ACTH in infants with West syndrome?

TZ Baram - Brain and Development, 2001 - Elsevier
A large body of experience has been compiled in different countries, documenting the
efficacy of adenocorticotropic hormone (ACTH) for infantile spasms. This is important …