[HTML][HTML] Brain perfusion estimation by Tikhonov model-free deconvolution in a long axial field of view PET/CT scanner exploring five different PET tracers
HBW Larsson, I Law, TL Andersen… - European Journal of …, 2024 - Springer
Purpose New total-body PET scanners with a long axial field of view (LAFOV) allow for
higher temporal resolution due to higher sensitivity, which facilitates perfusion estimation by …
higher temporal resolution due to higher sensitivity, which facilitates perfusion estimation by …
Bias in iterative reconstruction of low-statistics PET data: benefits of a resolution model
MD Walker, MC Asselin, PJ Julyan… - Physics in Medicine …, 2011 - iopscience.iop.org
Iterative image reconstruction methods such as ordered-subset expectation maximization
(OSEM) are widely used in PET. Reconstructions via OSEM are however reported to be …
(OSEM) are widely used in PET. Reconstructions via OSEM are however reported to be …
Quantitative cerebral H2 15O perfusion PET without arterial blood sampling, a method based on washout rate
V Treyer, M Jobin, C Burger, V Teneggi… - European journal of …, 2003 - Springer
The quantitative determination of regional cerebral blood flow (rCBF) is important in certain
clinical and research applications. The disadvantage of most quantitative methods using H 2 …
clinical and research applications. The disadvantage of most quantitative methods using H 2 …
A noninvasive method for quantifying cerebral blood flow by hybrid PET/MRI
T Ssali, UC Anazodo, JD Thiessen… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Although PET with 15O-water is the gold standard for imaging cerebral blood flow (CBF),
quantification requires measuring the arterial input function (AIF), which is an invasive and …
quantification requires measuring the arterial input function (AIF), which is an invasive and …
[HTML][HTML] Validation of kinetic modeling of [15O] H2O PET using an image derived input function on hybrid PET/MRI
MB Vestergaard, OP Calvo, AE Hansen, S Rosenbaum… - Neuroimage, 2021 - Elsevier
In present study we aimed to validate the use of image-derived input functions (IDIF) in the
kinetic modeling of cerebral blood flow (CBF) measured by [15 O] H 2 O PET by comparing …
kinetic modeling of cerebral blood flow (CBF) measured by [15 O] H 2 O PET by comparing …
[HTML][HTML] Brain perfusion CT compared with15OH2O-PET in healthy subjects
JM Grüner, R Paamand, L Højgaard, I Law - EJNMMI research, 2011 - Springer
Background Regional cerebral blood flow [rCBF] measurements are valuable for identifying
angiogenically active tumours, and perfusion computed tomography [CT] has been …
angiogenically active tumours, and perfusion computed tomography [CT] has been …
[HTML][HTML] Image-derived input functions from dynamic 15O–water PET scans using penalised reconstruction
P Young, L Appel, A Tolf, S Kosmidis, J Burman… - EJNMMI physics, 2023 - Springer
Background Quantitative positron emission tomography (PET) scans of the brain typically
require arterial blood sampling but this is complicated and logistically challenging. One …
require arterial blood sampling but this is complicated and logistically challenging. One …
[HTML][HTML] Non-invasive kinetic modelling approaches for quantitative analysis of brain PET studies
CWJ Van Der Weijden, P Mossel, AL Bartels… - European Journal of …, 2023 - Springer
Pharmacokinetic modelling with arterial sampling is the gold standard for analysing dynamic
PET data of the brain. However, the invasive character of arterial sampling prevents its …
PET data of the brain. However, the invasive character of arterial sampling prevents its …
Experimental and clinical evaluation of iterative reconstruction (OSEM) in dynamic PET: quantitative characteristics and effects on kinetic modeling
R Boellaard, A Van Lingen… - Journal of Nuclear …, 2001 - Soc Nuclear Med
The purpose of this study was to investigate the quantitative properties and effects of
ordered-subset expectation maximization (OSEM) on kinetic modeling compared with …
ordered-subset expectation maximization (OSEM) on kinetic modeling compared with …
Measurement of Cerebral Perfusion Indices from the Early Phase of [18F] MK6240 Dynamic Tau PET Imaging
6-(fluoro-18F)-3-(1H-pyrrolo [2, 3-c] pyridin-1-yl) isoquinolin-5-amine ([18F] MK6240) has
high affinity and selectivity for hyperphosphorylated tau and readily crosses the blood–brain …
high affinity and selectivity for hyperphosphorylated tau and readily crosses the blood–brain …