Objective: Discuss the molecular mechanism for improving neural regeneration after repair
of sciatic nerve defect in rat by acellular nerve allograft (ANA). Methods: Randomly divide 36 …

Background Schwann cells (SC) which are myelin-forming cells in peripheral nervous
system are very useful for the treatment of diseases of peripheral nervous system and …

Transplantation of adipose-derived mesenchymal stem cells (ASCs) induces tissue
regeneration by accelerating the growth of blood vessels and nerve. However, mechanisms …

Traumatic brain injuries and degenerative neurological disorders such as Alzheimer's
dementia, Parkinson's disease, amyotrophic lateral sclerosis and many others are …

Spinal cord injury (SCI), usually resulting in severe sensory and motor deficits, is a major
public health concern. Adipose‑derived stem cells (ADSCs), one type of adult stem cell, are …

Peripheral nerve damage is a significant clinical problem with limited therapeutic options.
Adipose-derived mesenchymal stem cells (ADSCs) have emerged as a promising …

In regenerative medicine applications, the differentiation stage of implanted stem cells must
be optimized to control cell fate and enhance therapeutic efficacy. We investigated the …

Through a combination of biomaterials and stem cells, tissue engineering strategies for
restoring and regenerating damaged peripheral nerves have recently been used to meet the …

Background Peripheral nerve injury (PNI) is one of the essential causes of physical disability
with a high incidence rate. The traditional tissue engineering strategy, Top-Down strategy …

Background Trauma-associated peripheral nerve injury is a widespread clinical problem
causing sensory and motor disabilities. Schwann cells (SCs) contribute to nerve …