Genetic influences have an important role in the ageing process. The genetic factors that
influence success in bodily ageing may also contribute to the successful ageing of cognitive …

The genetic protective factors for cognitive decline in aging remain unknown. Predicting an
individual's rate of cognitive decline—or with better cognitive resilience—using genetics will …

Human longevity and personality traits are both heritable and are consistently linked at the
phenotypic level. We test the hypothesis that candidate genes influencing longevity in lower …

In this study we explored the association between aging-related phenotypes previously
reported to predict survival in old age and variation in 77 genes from the DNA repair …

Ample evidence from model organisms has indicated that subtle variation in genes can
dramatically influence lifespan. The key genes and molecular pathways that have been …

There is an intense search for longevity genes in both animal models and humans. Human
family studies have indicated that a modest amount of the overall variation in adult lifespan …

With the increase of life expectancy, the world's population is aging rapidly. Previous work in
the field of aging greatly increases our understanding of biological mechanisms underlying …

Unbiased genome-wide studies of longevity in S. cerevisiae and C. elegans have led to the
identification of more than one hundred genes that determine life span in one or both …

Background Non-pathological cognitive ageing is a distressing condition affecting an
increasing number of people in our'ageing society'. Oxidative stress is hypothesised to have …

Studies in invertebrate model organisms have been a driving force in aging research,
leading to the identification of many genes that influence life span. Few of these genes have …