Proinflammatory cytokines in heart disease

CA Dinarello, BJ Pomerantz - Blood purification, 2001 - karger.com
Proinflammatory cytokines affect nearly all tissues and organ systems, and the vasculature is
no exception. Although a considerable amount of research has focused on the role of the …

Role of cytokines in myocardial ischemia and reperfusion

HS Sharma, DK Das - Mediators of inflammation, 1997 - Wiley Online Library
Mediators of myocardial inflammation, predominantly cytokines, have for many years been
implicated in the healing processes after infarction. In recent years, however, more attention …

Status of cytokines in ischemia reperfusion induced heart injury

M Zhang, L Chen - Cardiovascular & Haematological Disorders …, 2008 - ingentaconnect.com
Extensive investigations have implicated cytokines such as tumour necrosis factor (TNF)-α
and interleukin (IL)-1, and IL-6 as contributing to the pathology of ischemia-reperfusion (I/R) …

Effect of inflammatory mediators on cardiovascular function

U Mueller-Werdan, R Prondzinsky… - Current opinion in …, 2016 - journals.lww.com
Effect of inflammatory mediators on cardiovascular function : Current Opinion in Critical Care
Effect of inflammatory mediators on cardiovascular function : Current Opinion in Critical Care …

[HTML][HTML] Role of tumour necrosis factor-alpha and other cytokines in ischemia-reperfusion-induced injury in the heart

HK Saini, YJ Xu, M Zhang, PP Liu… - … & Clinical Cardiology, 2005 - ncbi.nlm.nih.gov
BACKGROUND: Several investigations have implicated cytokines such as tumour necrosis
factor-alpha (TNF-α), interleukin (IL)-1, IL-6, IL-8 and transforming growth factor-beta in the …

Inflammation in coronary artery disease and acute myocardial infarction-is the stage set for novel therapies?

R Klingenberg, TF Luscher - Current pharmaceutical design, 2012 - ingentaconnect.com
Acute myocardial infarction (AMI) constitutes the major cause of death in most nations and
death rates and morbidity remain substantial in the years thereafter. Inflammation is a …

A review of interleukin-1 in heart disease: where do we stand today?

Y Szekely, Y Arbel - Cardiology and therapy, 2018 - Springer
Cardiovascular diseases are the leading cause of death worldwide. Research in the last two
decades has emphasized the inflammatory process as a key component in the …

Endogenous cytokine antagonists during myocardial ischemia and thrombolytic therapy

L Airaghi, M Lettino, MG Manfredi, JM Lipton… - American Heart …, 1995 - Elsevier
We tested the idea that cytokine antagonists are released during acute myocardial ischemia
to counteract proinflammatory effects of cytokines. We investigated changes in plasma …

Tumor necrosis factor-α in cardiovascular biology and the potential role for anti-tumor necrosis factor-α therapy in heart disease

MN Sack - Pharmacology & therapeutics, 2002 - Elsevier
The functional role of tumor necrosis factor (TNF)-α in the heart has been extensively studied
over the last 15 years. Collectively, these studies have demonstrated that TNF-α has both …

The utility of anti-inflammatory agents in cardiovascular disease: a novel perspective on the treatment of atherosclerosis

SJ Kottoor, RR Arora - Journal of cardiovascular …, 2018 - journals.sagepub.com
Approximately 40% of heart attack survivors remain at increased risk of recurrent
cardiovascular events, despite the current treatment options showing that atherothrombosis …