Optimising microstructural characterisation of white-matter phantoms: impact of gradient waveform modulation on Non-uniform Oscillating Gradient Spin-Echo …

ML Gimenez, P Jimenez, LAP Perez… - arXiv preprint arXiv …, 2024 - arxiv.org
Changes in the nervous system due to neurological diseases take place at very small spatial
scales, on the order of the micro and nanometers. Developing non-invasive imaging …

[HTML][HTML] Selective filters of translational molecular diffusion dynamics in white matter microstructures with preclinical and clinical MRI. Submitted to the Intl

EL Saidman, A Zwick, S Tambalo… - Soc. Mag. Reson …, 2023 - index.mirasmart.com
Magnetic resonance imaging is one of the most widely used methods for non-invasive
medical imaging. Gradient modulation sequences can selectively extract quantitative …

Improved gradient waveforms for oscillating gradient spin‐echo (OGSE) diffusion tensor imaging

F Hennel, ES Michael, KP Pruessmann - NMR in Biomedicine, 2021 - Wiley Online Library
The dependence of the diffusion tensor on frequency is of great interest in studies of tissue
microstructure because it reveals restrictions to the Brownian motion of water molecules …

[HTML][HTML] Strong diffusion gradients allow the separation of intra-and extra-axonal gradient-echo signals in the human brain

E Kleban, CMW Tax, US Rudrapatna, DK Jones… - NeuroImage, 2020 - Elsevier
The quantification of brain white matter properties is a key area of application of Magnetic
Resonance Imaging (MRI), with much effort focused on using MR techniques to quantify …

[HTML][HTML] Cumulant expansion framework for internal gradient distributions tensors

LAP Pérez, GA Álvarez - Journal of Magnetic Resonance Open, 2023 - Elsevier
Magnetic resonance imaging is a powerful, non invasive tool for medical diagnosis. The low
sensitivity for detecting the nuclear spin signals, typically limits the image resolution to …

[HTML][HTML] Microstructure size-distribution estimations with smooth and sharp non-uniform oscillating gradient spin-echo modulations

ML Giménez, P Jiménez… - Proceedings of the …, 2018 - index.mirasmart.com
Morphological changes related to neurological diseases occur at micrometer scales.
Obtaining such information non-invasively opens new paradigms for clinical diagnosis. We …

[HTML][HTML] Diffusion MRI with free gradient waveforms on a high-performance gradient system: Probing restriction and exchange in the human brain

A Chakwizira, A Zhu, T Foo, CF Westin… - NeuroImage, 2023 - Elsevier
The dependence of the diffusion MRI signal on the diffusion time carries signatures of
restricted diffusion and exchange. Here we seek to highlight these signatures in the human …

In vivo investigation of restricted diffusion in the human brain with optimized oscillating diffusion gradient encoding

AT Van, SJ Holdsworth… - Magnetic resonance in …, 2014 - Wiley Online Library
Purpose Previous studies in phantoms and animals using animal MR systems have shown
promising results in using oscillating gradient spin echo (OGSE) diffusion acquisition to …

Diffusion weighted imaging with circularly polarized oscillating gradients

H Lundell, CK Sønderby… - Magnetic resonance in …, 2015 - Wiley Online Library
Purpose The short diffusion time regime provides an interesting probe for tissue
microstructure and can be investigated with oscillating gradient spin echo (OGSE) …

Measuring small compartment dimensions by probing diffusion dynamics via Non-uniform Oscillating-Gradient Spin-Echo (NOGSE) NMR

N Shemesh, GA Álvarez, L Frydman - Journal of magnetic resonance, 2013 - Elsevier
Noninvasive measurements of microstructure in materials, cells, and in biological tissues,
constitute a unique capability of gradient-assisted NMR. Diffusion–diffraction MR …