BACKGROUND The optimal treatment strategy for patients with clinical stage I (CS‐1)
seminoma is controversial. The objective of the current study was to evaluate the outcomes …

BACKGROUND The majority of germ cell tumour (GCT) patients can be cured by
orchiectomy followed by active surveillance or subsequent systemic and/or local treatments …

ACT has been shown to be non-inferior to ART [6]. In the largest series of ACT, a 4.1%
relapse rate was demonstrated with a median time to relapse of 22.7 months among 517 …

Background As the characteristics and outcome associated with relapse in seminomatous
testicular germ cell tumors are still unclear, this study aims at evaluating the differences …

TO THE EDITOR: In their editorial1 accompanying our article, 2 Bosl and Patil make a
number of incorrect assertions which require a response. The majority of these issues relate …

Background Testicular cancer is primarily treated with the surgical removal of the affected
testis. About 50% of testicular cancer patients present with a stage I seminoma. If no chemo …

Background Outcomes for men with stage I seminoma are excellent and avoiding intensive
chemotherapy in these young patients is important. CT surveillance is a standard of care …

Objective Testicular stage I seminoma has a remarkable cure rate with orchiectomy alone.
The benefit of adjuvant therapy is questionable, and a direct comparison with active …

Aims Stage II testicular seminoma is highly curable with radiotherapy or multi-agent
chemotherapy (MACT). These modalities have not been compared in a randomised manner …

Purpose: Among the adjuvant options to be proposed to patients with stage I seminoma after
orchiectomy, the administration of a single cycle of carboplatin, at the dosage reaching an …