A comprehensive review of observational pertussis vaccine effectiveness (VE) studies is
needed to update gaps from previous reviews. We conducted a systematic review of VE and …

Background. Booster vaccination against tetanus and diphtheria at 10-year intervals is
commonly recommended. Reduced antigen content diphtheria and tetanus toxoids and …

Pertussis is a highly contagious disease, for which periodic peaks in incidence and an
increasing number of outbreaks have been observed over the last decades. The reduced …

Background. Unexpected waning of immunity after pertussis vaccination is now well
described. In this study we examined whether prior vaccination with whole-cell pertussis …

Purpose: To examine recent evidence concerning the health benefits and cost effectiveness
of replacing a single dose of adult tetanus/diphtheria vaccine with a single dose of …

Pertussis is an important cause of morbidity and mortality, and its incidence has been
increasing in adolescents and adults over the past two decades. Waning immunity in …

An understanding of the antibody persistence elicited by a combined tetanus, diphtheria, 5-
component acellular pertussis, and inactivated poliovirus vaccine (Tdap-IPV) after …

Background. Published data on the safety of tetanus-diphtheria-acellular pertussis vaccine
(Tdap) in persons aged≥ 65 years are limited. This study aims to examine a large cohort of …

The recent increase of pertussis in young adults in Japan is hypothesized to be due in part
to waning protection from the acellular pertussis vaccine. While a booster immunization may …

BACKGROUND: Although decennial adult boosters of tetanus and diphtheria toxoids are
recommended in Canada and the United States, a second dose of pertussis vaccine is not …