As exemplified by the recent clinical success of immune checkpoint blockers (ICBs) and
chimeric antigen receptor (CAR) T-cell therapy, cancer immunotherapy is heralded as the …

Although the ever-increasing number of cancer patients pose substantial challenges
worldwide, finding a treatment with the highest response rate and the lowest number of side …

Targeting of the immune system has shown to be a successful therapeutic approach in
cancer, with the development of check point inhibitors (ICI) or T-cell engagers (TCE). As …

Cancer immunotherapy has reached a critical point, now that immune checkpoint inhibitors
and two CAR-T products have received market approval in treating 16 types of cancers and …

The advent of novel immunotherapies in the treatment of cancers has dramatically changed
the landscape of the oncology field. Recent developments in checkpoint inhibition therapies …

Immune checkpoint molecules are a group of molecules expressed on the surface of
immune cells that primarily regulate their immune homeostasis. Chimeric antigen receptor …

ABSTRACT With the Nobel Prize in Physiology or Medicine in 2018, cancer immunotherapy
is attracting more attention than ever before and is strongly expected to develop in the future …

The fast evolution of anti-tumor agents embodies a deeper understanding of cancer
pathogenesis. To date, chemotherapy, targeted therapy, and immunotherapy are three …

Conspectus Immunotherapy has attracted significant interest because of its tremendous
potential in cancer therapy. The recent advances in the identification of cancer-associated …

In recent years, the impressive number of cancer immunotherapy drugs approved has been
unprecedented—building on over a century of understanding on how the immune system …