[HTML][HTML] Early environmental enrichment and impoverishment differentially affect addiction-related behavioral traits, cocaine-taking, and dopamine D2/3 receptor …
L Bellés, A Dimiziani, FR Herrmann, N Ginovart - Psychopharmacology, 2021 - Springer
Rationale Risk factors for drug addiction include genetics, environment, and behavioral traits
such as impulsivity and novelty preference (NP), which have been related to deficits in …
such as impulsivity and novelty preference (NP), which have been related to deficits in …
[HTML][HTML] Repeated Cocaine Intake Differentially Impacts Striatal D2/3 Receptor Availability, Psychostimulant-Induced Dopamine Release, and Trait Behavioral …
G Urueña-Méndez, A Dimiziani, L Bellés… - International Journal of …, 2023 - mdpi.com
Current research indicates that altered dopamine (DA) transmission in the striatum
contributes to impulsivity and novelty-seeking, and it may mediate a link concerning a higher …
contributes to impulsivity and novelty-seeking, and it may mediate a link concerning a higher …
Different effects of chronic THC on the neuroadaptive response of dopamine D2/3 receptor‐mediated signaling in roman high‐and roman low‐avoidance rats
The Roman high (RHA)‐and low (RLA)‐avoidance rat sublines have been identified as an
addiction‐prone and addiction‐resistant phenotype based on their high vs. low locomotor …
addiction‐prone and addiction‐resistant phenotype based on their high vs. low locomotor …
Innately low D2 receptor availability is associated with high novelty-seeking and enhanced behavioural sensitization to amphetamine
BB Tournier, T Steimer, P Millet… - International Journal …, 2013 - academic.oup.com
High novelty-seeking has been related to an increased risk for developing addiction, but the
neurobiological mechanism underlying this relationship is unclear. We investigated whether …
neurobiological mechanism underlying this relationship is unclear. We investigated whether …
Dopamine D2/3 Receptor Availabilities and Evoked Dopamine Release in Striatum Differentially Predict Impulsivity and Novelty Preference in Roman High- and Low …
L Bellés, A Dimiziani, S Tsartsalis… - International Journal …, 2021 - academic.oup.com
Background Impulsivity and novelty preference are both associated with an increased
propensity to develop addiction-like behaviors, but their relationship and respective …
propensity to develop addiction-like behaviors, but their relationship and respective …
Differential involvement of D2 and D3 receptors during reinstatement of cocaine-seeking behavior in the Roman high-and low-avoidance rats.
A Dimiziani, L Bellés Añó, S Tsartsalis… - Behavioral …, 2019 - psycnet.apa.org
Roman high-(RHA) and low-avoidance (RLA) rats have been used as a model for drug-
addiction, showing, respectively, high-and low-responding to psychostimulants, and low …
addiction, showing, respectively, high-and low-responding to psychostimulants, and low …
Social and physical environment alter cocaine conditioned place preference and dopaminergic markers in adolescent male rats
E Zakharova, J Miller, E Unterwald, D Wade… - Neuroscience, 2009 - Elsevier
This study was done to determine whether social and environmental factors alter cocaine
reward and proteins implicated in mediating drug reward in rats during early adolescence …
reward and proteins implicated in mediating drug reward in rats during early adolescence …
Environment‐dependent behavioral traits and experiential factors shape addiction vulnerability
M Fouyssac, M Puaud, E Ducret… - European Journal of …, 2021 - Wiley Online Library
The transition from controlled drug use to drug addiction depends on an interaction between
a vulnerable individual, their environment and a drug. Here we tested the hypothesis that …
a vulnerable individual, their environment and a drug. Here we tested the hypothesis that …
Distinct effects of enriched environment on dopamine clearance in nucleus accumbens shell and core following systemic nicotine administration
J Zhu, MT Bardo, LP Dwoskin - Synapse, 2013 - Wiley Online Library
Environmental enrichment during development may reduce drug abuse liability by
modulating dopamine transporter (DAT) function. Nucleus accumbens (NAc) shell and core …
modulating dopamine transporter (DAT) function. Nucleus accumbens (NAc) shell and core …
Adolescent social defeat increases adult amphetamine conditioned place preference and alters D2 dopamine receptor expression
Components of the brain's dopaminergic system, such as dopamine receptors, undergo final
maturation in adolescence. Exposure to social stress during human adolescence contributes …
maturation in adolescence. Exposure to social stress during human adolescence contributes …