A genetically determined host factor controlling susceptibility to encephalomyocarditis virus-induced diabetes in mice

Y Kang, JW Yoon - Journal of general virology, 1993 - microbiologyresearch.org
Levels of insulin mRNA in pancreata from SJL/J male mice susceptible to
encephalomyocarditis (EMC)-D virus-induced diabetes started to decrease rapidly 24 h after …

Differing attachment of diabetogenic and nondiabetogenic variants of encephalomyocarditis virus to β-cells

PE Kaptur, DC Thomas, DJ Giron - Diabetes, 1989 - Am Diabetes Assoc
The D variant of encephalomyocarditis (EMC-D) virus does not induce the production of
interferon (IFN) and produces an insulin-dependent diabetes mellitus (IDDM)-like syndrome …

Encephalomyocarditis virus-induced diabetes mellitus in mice: model of viral pathogenesis

GW Jordan, SH Cohen - Reviews of infectious diseases, 1987 - academic.oup.com
Encephalomyocarditis (EMC) virus induction of diabetes mellitus in mice has proven to bean
excellent experimental model for the pathogenesis of viral disease. In SJL and DBA/2 mice …

The significance of T cells, B cells, antibodies and macrophages against encephalomyocarditis (EMC)-D virus-induced diabetes in mice

E Kounoue, K Izumi, S Ogawa, S Kondo, H Katsuta… - Archives of …, 2008 - Springer
In order to clarify the significance of protective mechanisms against encephalomyocarditis
(EMC) virus-induced diabetes in mice, we studied the relative importance of T cells, B cells …

Encephalomyocarditis virus and diabetes mellitus: studies on virus mutants in susceptible and non-susceptible mice

JP Kruppenbacher, TH Mertens… - Journal of general …, 1985 - microbiologyresearch.org
The so-called M-variant (especially subtype D) of encephalomyocarditis virus (EMCV)
induces a diabetes-like syndrome in certain mouse strains which may serve as a model of …

Genetic influences on the immunologic pathogenesis of encephalomyocarditis (EMC) virus-induced diabetes mellitus

SA Huber, PG Babu, JE Craighead - Diabetes, 1985 - Am Diabetes Assoc
DBA/2 and Balb/cBY mice were infected with approximately 30 plaque-forming units of the M-
variant of encephalomyocarditis (EMC-M) virus. Seven days after inoculation the majority of …

Virus-induced diabetes mellitus: IV. Genetic and environmental factors influencing the development of diabetes after infection with the M variant of …

ME Ross, T Onodera, KS Brown, AL Notkins - Diabetes, 1976 - Am Diabetes Assoc
The M variant of encephalomyocarditis virus (EMC) infects pancreatic beta cells and causes
the development of a diabetic syndrome in susceptible strains of mice. By examining four F1 …

Replication of diabetogenic and nondiabetogenic variants of encephalomyocarditis (EMC) virus in ICR Swiss mice

CL Gould, ML Trombley, NJ Bigley… - Proceedings of the …, 1984 - journals.sagepub.com
The replication of the diabetogenic D (EMC-D) and nondiabetogenic B (EMC-B) variants of
encephalomyocarditis virus in various tissues of the murine host was determined. Pancreatic …

Altered pathogenesis in encephalomyocarditis virus (D variant)-infected diabetes-susceptible and resistant strains of mice

KL Gaines, SG Kayes, GL Wilson - Diabetologia, 1986 - Springer
The D variant of encephalomyocarditis virus (EMCV-D) induces a diabetes mellitus-like
disease in male SJL/J mice. Other inbred strains, while resistant to the diabetogenic effect …

Virus-induced diabetes mellitus

JW Yoon, PR McClintock, T Onodera, AL Notkins - J. Exp. Med, 1980 - ncbi.nlm.nih.gov
Beta cells were isolated from strains of mice that were susceptible and resistant to
encephalomyocarditis (EMC) viral-induced diabetes mellitus. Beta cells from susceptible …