Antimicrobial resistance is a major global health challenge. As few new efficacious
antibiotics will become available in the near future, peptide antibiotics continue to be major …

As bacterial resistance continues to increase, optimising the potential for successful clinical
outcomes with antimicrobial therapy requires consideration of pharmacodynamic concepts …

There is a growing need to optimize the use of old and new antibiotics to treat serious as
well as less serious infections. The topic of how to use pharmacokinetic and …

The antimicrobial resistance crisis is an ongoing major threat to public health safety. Low-
and middle-income countries are particularly susceptible to higher fatality rates and the …

Among other health related issues, the rising concerns on drug resistance led to look for
alternative pharmaceutical drugs that are effective both against infectious and noninfectious …

Whereas infections caused by multidrug-resistant micro-organisms are increasing
worldwide, there are few new molecules, especially ones that are active against Gram …

When evaluating the efficacy of antibiotics for the treatment of respiratory tract infections,
such as community acquired pneumonia and acute exacerbations of chronic bronchitis …

Antimicrobial peptides (AMPs) attack bacterial membranes selectively, killing microbes at
concentrations that cause no toxicity to the host cells. This selectivity is not due to interaction …

Antibiotic resistance presents an incessant threat to our drug armamentarium that
necessitates novel approaches to therapy. Over the past several decades, investigation of …

A deep understanding of an antimicrobial's critical pharmacokinetic and pharmacodynamic
properties is crucial towards optimizing its use in patients and bolstering the drug …