Rituximab has emerged as an effective and important therapy in children with complicated
frequently relapsing and steroid-dependent nephrotic syndrome to induce long-term disease …

Objective Rituximab is an effective treatment for children with steroid dependent or
frequently relapsing nephrotic syndrome. The optimum dosing schedule for rituximab has …

The idiopathic nephrotic syndrome (ie MCNS and FSGS) in children has been regarded as a
disorder of T-cell function. Recent studies, however, also describe abnormalities of B-cell …

Background Approximately 30% of children with idiopathic nephrotic syndrome develop a
complicated course with frequent relapses or steroid dependency. Rituximab, a B cell …

Ravani et al. report that rituximab is a safe and effective steroid-sparing and calcineurin-
inhibitor-sparing agent in 46 children with idiopathic nephrotic syndrome over a median …

Background Rituximab has emerged as an important medication for patients with steroid-
dependent or steroid-resistant nephrotic syndrome. Patients We report the efficacy and …

Patients with steroid-resistant nephrotic syndrome (SRNS) who develop resistance to
immunosuppressive agents, defined as refractory SRNS, have poor renal outcomes …

Although most patients with idiopathic nephrotic syndrome (NS) respond to steroid
treatment, development of steroid dependency may require a long-term multidrug therapy …

Objectives: Rituximab (RTX) is a new treatment option in children with difficult-to-treat steroid-
dependent nephrotic syndrome (SDNS). We evaluated the experience of our tertiary center …

Rituximab is an effective treatment for steroid-dependent/frequently-relapsing nephrotic
syndrome (SDFRNS) in children. However, the optimal rituximab regimen remains unknown …