Dendritic-cell-based therapeutic vaccination against cancer
FO Nestle, A Farkas, C Conrad - Current opinion in immunology, 2005 - Elsevier
Early clinical trials, in which over 1000 cancer patients received dendritic cell (DC) vaccines,
tested different vaccine preparations, but they did not always induce sufficient acquired …
tested different vaccine preparations, but they did not always induce sufficient acquired …
Dendritic cell–based immunotherapy: state of the art and beyond
KF Bol, G Schreibelt, WR Gerritsen, IJM De Vries… - Clinical cancer …, 2016 - AACR
Dendritic cell (DC) vaccination in cancer patients aims to induce or augment an effective
antitumor immune response against tumor antigens and was first explored in a clinical trial …
antitumor immune response against tumor antigens and was first explored in a clinical trial …
[HTML][HTML] Dendritic cells in anticancer vaccination: rationale for ex vivo loading or in vivo targeting
AV Baldin, LV Savvateeva, AV Bazhin, AA Zamyatnin Jr - Cancers, 2020 - mdpi.com
Dendritic cells (DCs) have shown great potential as a component or target in the landscape
of cancer immunotherapy. Different in vivo and ex vivo strategies of DC vaccine generation …
of cancer immunotherapy. Different in vivo and ex vivo strategies of DC vaccine generation …
Clinical application of dendritic cells in cancer vaccination therapy
IM Svane, ML Soot, S Buus, HE Johnsen - Apmis, 2003 - Wiley Online Library
During the last decade use of dendritic cells (DC) has moved from murine and in vitro
studies to clinical trials as adjuvant in cancer immunotherapy. Here they function as delivery …
studies to clinical trials as adjuvant in cancer immunotherapy. Here they function as delivery …
[HTML][HTML] Dendritic cells in cancer vaccines
P Brossart, S Wirths, W Brugger, L Kanz - Experimental hematology, 2001 - Elsevier
Dendritic cells (DC) are recognized as the most potent antigen-presenting cells with the
ability to stimulate naive resting T cells and to initiate primary immune responses …
ability to stimulate naive resting T cells and to initiate primary immune responses …
Dendritic cells as cancer therapeutics
CE Bryant, S Sutherland, B Kong… - Seminars in Cell & …, 2019 - Elsevier
The ability of immune therapies to control cancer has recently generated intense interest.
This therapeutic outcome is reliant on T cell recognition of tumour cells. The natural function …
This therapeutic outcome is reliant on T cell recognition of tumour cells. The natural function …
[HTML][HTML] Recent advances in experimental dendritic cell vaccines for cancer
The development of immunotherapeutic methods for the treatment of oncological diseases
have made it possible to improve the effectiveness of standard therapies. There was no …
have made it possible to improve the effectiveness of standard therapies. There was no …
[HTML][HTML] Dendritic cells in cancer immunotherapy clinical trials: are we making progress?
LH Butterfield - Frontiers in immunology, 2013 - frontiersin.org
Dendritic cells (DC) have been tested in cancer immunotherapy clinical trials for two
decades. Over this time, the methods of DC culture (or manufacture) have evolved, the …
decades. Over this time, the methods of DC culture (or manufacture) have evolved, the …
Therapeutic Dendritic Cell− Based Cancer Vaccines: The State of the Art
MM Strioga, T Felzmann, DJ Powell Jr… - Critical Reviews™ in …, 2013 - dl.begellhouse.com
Dendritic cells (DCs) are the most potent professional antigen-presenting cells, capable of
initiating proper adaptive immune responses. Although tumor-infiltrating DCs are able to …
initiating proper adaptive immune responses. Although tumor-infiltrating DCs are able to …
[HTML][HTML] The clinical application of cancer immunotherapy based on naturally circulating dendritic cells
Dendritic cells (DCs) can initiate and direct adaptive immune responses. This ability is
exploitable in DC vaccination strategies, in which DCs are educated ex vivo to present tumor …
exploitable in DC vaccination strategies, in which DCs are educated ex vivo to present tumor …