Background A new strategy is introduced combining the use of Multi-Criteria Optimization-
based Trade-Off Exploration (TO) and RapidPlan™(RP) for the selection of optimisation …

Objectives This report is an update of a Comparative Effectiveness Review (CER) published
in final form in May 2010 on the benefits and harms of radiotherapy (RT) to treat patients with …

Improving the conformity of the radiation dose to targets in the head and neck promises
reduced toxicity and, in some cases, potentially improved local-regional tumor control …

Purpose: To investigate whether intensity-modulated radiation therapy (IMRT) allows more
mucosal sparing than standard three-field technique (3FT) radiotherapy for early …

Purpose Few studies have reported large inter-observer variations in target volume
selection and delineation in patients treated with radiotherapy for head and neck squamous …

Results Remarkable heterogeneity in H&N IMRT design and practice was identified in this
international study. Treatment Targets: Two thirds of responders would treat the primary …

Purpose The required elective nodal dose and volumes for head and neck intensity
modulated radiation therapy have largely been extrapolated from conventional radiation …

PURPOSE: To evaluate the variability of organ at risk (OAR) delineation and the resulting
impact on intensity modulated radiation therapy (IMRT) treatment plan optimization in head …

PURPOSE: To determine if image-guided radiotherapy (IGRT) ensures dose coverage to the
target, and to assess the dosimetric impact of anatomic changes using megavoltage cone …

Purposes To generate a nomogram to predict parotid gland (PG) overdose and to quantify
the dosimetric benefit of weekly replanning based on its findings, in the context of intensity …