Background & aims Recent experimental models and epidemiological studies suggest that
specific environmental contaminants (ECs) contribute to the initiation and pathology of non …

Exposures to perfluoroalkyl substances (PFAS) including perfluoroalkyl acids (PFAAs) are
associated with increased liver enzymes in cohort studies including the C8 Health Study. In …

Background & Aims Per-and polyfluoroalkyl substances (PFAS) are widespread pollutants
with demonstrated hepatotoxicity. Few studies have examined the association between …

Background Non-alcoholic fatty liver disease (NAFLD) has become the leading cause of
chronic liver disease worldwide and the determinants driving its severity remain to be …

Background While it is known that perfluoroalkyl substances (PFASs) induce liver toxicity in
experimental studies, the evidence of an association in humans is inconsistent. Objective …

Background & Aims Exposure to poly-and perfluoroalkyl substances (PFAS), a class of
persistent organic pollutants, is ubiquitous. Animal studies suggest that PFAS may increase …

Background Perfluoroalkyl substances can disrupt hepatic metabolism and may be
associated with liver function biomarkers. We examined individual and mixture associations …

Background & Aims Accumulating animal studies have demonstrated the harmful
contribution of ambient air pollution (AP) to metabolic dysfunction-associated fatty liver …

Abstract Purpose of Review Environmental contaminants are considered one of the major
factors in the development and progression of NAFLD, the most common liver disease in the …

Persistent presence of perfluoroalkyl acids (PFAAs) in the environment is due to their
extensive use in industrial and consumer products, and their slow decay. Biochemical tests …