Can murine diabetic nephropathy be separated from superimposed acute renal failure?
Background Streptozotocin (STZ) is commonly used to induce diabetes in experimental …

Diabetic nephropathy (DN) is the leading cause of chronic kidney disease. Animal models
are essential tools for designing new strategies to prevent DN. C57Bl/6 (B6) mice are widely …

Streptozotocin‐induced pancreatic injury is commonly used for creating rodent models of
type 1 diabetes which develop renal injury with similarities to human diabetic nephropathy …

Background The animal model with streptozotocin (STZ)‐induced diabetes mellitus is
associated with progressive renal disturbances. The aim of this study was to differentiate …

Induction of streptozotocin (STZ) diabetes in hypertensive rats transgenic for the mouse ren-
2 gene (TGR) has been described as a model of progressive diabetic nephropathy. We …

The Streptozotocin‐(STZ‐) induced diabetic model is widely used; however, unexplained
acute toxicity has given the model an unreliable reputation. To improve the reliability and …

The Streptozotocin (STZ) model of diabetes is commonly used for studies of diabetic
nephropathy although the histological lesions of the kidney are mild and do not resemble …

The rat streptozotocin (STZ)-induced diabetes model is widely used to investigate the
pathogenesis of diabetic nephropathy. However, overt nephropathy is inexplicably slow to …

Diabetic nephropathy (DN) is the main factor leading to end‐stage renal disease (ESRD)
and subsequent morbidity and mortality. Importantly, the prevalence of DN is continuously …

Gene expression profile in streptozotocin-induced diabetic mice kidneys undergoing
glomerulosclerosis. Background To elucidate the molecular mechanism of diabetic …