Cognitive processes associated with prefrontal cortex and hippocampus decline with age
and are vulnerable to disruption by stress. The stress/stress hormone/allostatic load …

Aging is associated with altered sleep architecture and worsened hippocampus-dependent
cognition, highly prevalent clinical conditions that detract from quality of life for the elderly …

Stress-related psychopathology is highly prevalent among elderly individuals and is
associated with detrimental effects on mood, appetite and cognition. Conversely, under …

Neuronal networks in the prefrontal cortex mediate the highest levels of cognitive processing
and decision making, and the capacity to perform these functions is among the cognitive …

Coping is a strategic approach to dealing with stressful situations. Those who use proactive
coping strategies tend to accept changes and act before changes are expected. In contrast …

Age‐related cognitive decline is one of the major aspects that impede successful aging in
humans. Environmental factors, such as chronic stress, can accelerate or aggravate …

The glucocorticoid (GC) hypothesis posits that effects of stress and dysregulated
hypothalamic-pituitary-adrenal axis activity accumulate over the lifespan and contribute to …

Aging is associated with dysregulation of emotional and endocrine responses in a stressful
environment. To understand the developmental mechanisms of stress vulnerability with …

Exposure to chronic adverse conditions, and the resultant activation of the neurobiological
response cascade, has been associated with an increased risk of early onset of age-related …

Clinical findings reveal that middle-aged patients are more susceptible to suffer from
psychiatric disorders than older ones. However, little is known about the emotional behavior …