Although the pharmacological activity of capsaicin has been explained by its specific
binding to transient receptor potential vanilloid type 1, the amphiphilic structure of capsaicin …

Capsaicin is a natural compound that produces a warm sensation and is known for its
remarkable medicinal properties. Understanding the interaction between capsaicin with lipid …

Capsaicin is the chemical responsible for making some peppers spicy hot, but additionally it
is used as a pharmaceutical to alleviate different pain conditions. Capsaicin binds to the …

At submicromolar concentrations, capsaicin specifically activates the TRPV1 receptor
involved in nociception. At micro-to millimolar concentrations, commonly used in clinical and …

Capsaicin has been touted as a pharmacological tool specific for sensory afferent neurons
and is widely used in neurophysiological studies. However, we have recently demonstrated …

Capsaicin (CAP) excites small sensory neurons, causing pain, neurogenic inflammation,
and other visceral reflexes. These effects have been proposed to be the result of CAP …

Capsaicin is an ingredient of a wide variety of red peppers, and it has various
pharmacological and biological applications. The present study explores the interaction of …

Capsaicin is a natural compound with pharmacological and toxicological effects, which
given its hydrophobicity, can influence the structure of membranes. The interaction of …

Capsaicin (CAP)-activated ion channel plays a key role in generating nociceptive neural
signals in sensory neurons. Here we present evidence that intracellular ATP upregulates the …

THE function of primary afferent neurons is to receive and transmit information from the
internal and external environment and thereby contribute to the organism's ability to …