Termination of transcription by RNA polymerase II (Pol II) is a poorly understood yet
essential step in eukaryotic gene expression. Termination of pre-mRNA synthesis is coupled …

RNA polymerase II (Pol II) termination is triggered by sequences present in the nascent
transcript. Termination of pre-mRNA transcription is coupled to recognition of cis-acting …

Most eukaryotic genes are transcribed by RNA polymerase II (Pol II), including those that
produce mRNAs and many noncoding functional RNAs. Proper expression of these genes …

RNA polymerase II transcribes both protein coding and non-coding RNA genes and, in
yeast, different mechanisms terminate transcription of the two gene types. Transcription …

Transcription termination at mRNA genes is linked to polyadenylation. Cleavage at the poly
(A) site generates an entry point for the Rat1/Xrn2 exonuclease, which degrades the …

The C-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) serves an
important role in coordinating stage-specific recruitment and release of cellular machines …

RNA polymerase II synthesizes a diverse set of transcripts including both protein-coding and
non-coding RNAs. One major difference between these two classes of transcripts is the …

The yeast RNA binding proteins Nrd1 and Nab3 are required for termination of
nonpolyadenylated transcripts from RNA polymerase (Pol) II-transcribed snRNA and …

Yeast RNA-binding proteins Nrd1 and Nab3 direct transcription termination of sn/snoRNA
transcripts, some mRNA transcripts, and a class of intergenic and anti-sense transcripts …

Transcription termination by RNA polymerase II is coupled to transcript 3′ end formation. A
large cleavage and polyadenylation complex containing the major poly (A) polymerase …