Colorectal cancers are among the most commonly found cancers over the world. In spite of
the recent advancements in diagnosis and prognosis, the management of this metastatic …

Despite being one of the most frequently diagnosed cancers worldwide, prognosis of
metastatic colorectal cancer (CRC) was poor. Development and introduction of biologic …

Colorectal cancer is one of the most common cancers worldwide and one of the leading
causes of cancer-related death in the Western world. Tumor progression towards metastasis …

Colorectal cancer (CRC) represents 10% of all cancer types, making it the third leading
cause of cancer-related deaths globally. Metastasis is the primary factor causing mortality in …

Purpose. The results of clinical trials that led to modern first-and second-line
chemotherapeutic regimens for metastatic colorectal cancer, including studies of recently …

Introduction: Outcomes in metastatic colorectal cancer are improving, with better
understanding and use of targeted therapies. Areas covered: A review of the literature and …

Colorectal cancer (CRC) is the third leading cause of cancer deaths, and while mortality has
largely improved in the developed world, five-year survival for metastatic disease remains …

Colorectal cancer (CRC) is the third most common type of cancer and the second leading
cause of cancer deaths worldwide. Surgery or surgery plus radiotherapy and/or …

Over the past 8 to 10 years, significant advances have been made in the treatment of
metastatic colorectal cancer (mCRC). In particular, the development of the targeted biologic …

Colorectal cancer (CRC) is among the most lethal and prevalent malignancies in the world
and was responsible for nearly 881,000 cancer-related deaths in 2018. Surgery and …