Alzheimer's disease (AD) is a complex age-related neurodegenerative disease, associated
with central and peripheral metabolic anomalies, such as impaired glucose utilization and …

Abstract Alzheimer's disease (AD), the most common type of senile dementia, is a chronic
neurodegenerative disease characterized by cognitive dysfunction and behavioral disability …

Background Old age, the most important risk factor for Alzheimer's disease (AD), is
associated with thermoregulatory deficits. Brown adipose tissue (BAT) is the main …

To maintain energy supply to the brain, a direct energy source called adenosine
triphosphate (ATP) is produced by oxidative phosphorylation and aerobic glycolysis of …

The sharp rise in the incidence of Alzheimer's disease (AD) at an old age coincides with a
reduction in energy metabolism and core body temperature. We found that the triple …

Clinical trials have extensively failed to find effective treatments for Alzheimer's disease (AD)
so far. Even after decades of AD research, there are still limited options for treating …

Objective Old age is associated with a rise in the incidence of Alzheimer's disease (AD) but
also with thermoregulatory deficits. Indicative of a link between the two, hypothermia induces …

Metabolic dysfunction is a well-established feature of Alzheimer's disease (AD), evidenced
by brain glucose hypometabolism that can be observed potentially decades prior to the …

Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder worldwide.
While the causes of AD are not known, several risk factors have been identified. Among …

Alzheimer's disease (AD) is a rapidly growing public health concern with potentially
devastating effects. Presently, there are no known cures or effective preventive strategies …