The aim of this study was to investigate effect of nitric oxide (NO) modulation on possible
nephroprotective mechanisms of nebivolol (NEB) in cyclosporine A (CsA)-induced …

The usefulness of cyclophosphamide (CP) in the treatment of multiple human malignancies
and immunological diseases is hindered by the danger of developing nephrotoxicity. The …

Abstract Background Cyclosporine A (CsA)-induced nephrotoxicity is a challenging problem
complicating its chronic use in a large array of autoimmune diseases, as well as in organ …

Abstract Treatment with cisplatin is associated with dose‐limiting side effects, mainly
nephrotoxicity. On the other hand, nebivolol, a β1‐adrenoceptor antagonist, exhibits …

Despite that cyclosporine-A (CsA) is a widely used immunosuppressive drug, its nephrotoxic
effect limits its long-term administration. Herein we tried to investigate its renal effect on …

Cyclosporine A (CsA) is a potent and effective immunosuppressive agent, but its use is
frequently accompanied by severe renal toxicity. The causes for the nephrotoxicity of CsA …

Indomethacin (INDO) is an NSAID with remarkable efficacy and widespread utilization for
alleviating pain. Nevertheless, renal function impairment is an adverse reaction linked to …

Background To evaluate the protective effect of nebivolol against kidney damage and
elucidate the underlying mechanism in a two-kidney, one-clip (2K1C) rat model. Methods …

Background Vancomycin (VCM) is used clinically to treat serious infections caused by multi-
resistant Gram-positive bacteria, although its use is severely constrained by nephrotoxicity …

Folic acid (FA)‐induced acute kidney injury (AKI) is a commonly used model in experimental
animals for studying renal injury. This study aimed to investigate the probable protecting …