The local environment surrounding airway smooth muscle (ASM) cells has profound effects
on the physiological and phenotypic properties of ASM tissues. ASM is continually subjected …

The local environment surrounding airway smooth muscle cells (ASM) has profound effects
on the physiologic and phenotypic properties of ASM tissues. ASM is continually subjected …

The ability of airway smooth muscle to alter its stiffness and contractility in response to
mechanical oscillation and stretch is critically important for the regulation of normal airway …

The airway smooth muscle from asthmatic airways produces increased amounts and an
altered composition of extracellular matrix proteins. The extracellular matrix can in turn …

The biological configuration of extracellular matrix (ECM) plays a key role in how
mechanical interactions of the airway with its parenchymal attachments affect the dynamics …

ECM as a critical regulator of all the known functions of ASM including contraction,
attachment and migration, apoptosis, proliferation and cytokine production. Alterations in the …

Asthma is characterized by structural changes in the airways–airway remodelling. These
changes include an increase in the bulk of the airway smooth muscle (ASM) and alterations …

Chronic asthma is an inflammatory airways disease characterized by pathological changes
in the airway smooth muscle (ASM) bundle that contribute to airway obstruction and …

Asthma as well as bronchiolitis obliterans and chronic bronchitis are chronic lung diseases
characterized by airflow obstruction and airway inflammation. Although asthma typically …

Airway structure and function are key aspects of normal lung development, growth, and
aging, as well as of lung responses to the environment and the pathophysiology of important …