Background and objectives One of the possible male sterility risk factors are polymorphisms
of Methylenetetrahydrofolate reductase (MTHFR). However, the epidemiologic …

The aim of the study was to analyze the distribution of the methylenetetrahydrofolate
reductase (MTHFR), methionine synthase reductase (MTRR), and methionine synthase …

In this paper, we evaluate the association of the human methylenetetrahydrofolate reductase
(MTHFR)-G1793A transition with male infertility using a case-control study, a meta-analysis …

Previous studies have revealed that genetic factors may be involved in regulating the
mechanism of infertility, eg, MTHFR gene polymorphism in the development of male …

Spermatogenesis is a process where an important contribution of genes involved in folate-
mediated one-carbon metabolism is observed. The aim of the present study was to …

Purpose This study explored the possible association of four single nucleotide
polymorphisms (SNPs) of the three folate-related enzyme genes: MTHFR C677T and …

Objective To investigate the association of polymorphisms in the folate-metabolizing genes
with idiopathic male infertility in a Russian population and to perform a meta-analysis …

Methylenetetrahydrofolate reductase (MTHFR) is a gene involved in the process of DNA
synthesis and methylation. The MTHFR C677T polymorphism has been associated with …

Several studies showed that the genetic mutations in the folate-related enzyme genes might
be associated with male infertility; however, the results were still inconsistent. We performed …

OBJECTIVE: To determine the frequency of C677T methylenetetrahydrofolate reductase
(MTHFR) polymorphism in fertile and subfertile males, and the MTHFR-dependent response …