Nephropathy is a serious complication of metabolic syndrome (MS), a global epidemic
disorder. This study was undertaken to investigate the actions of diosmin and crocin, two …

Diabetic Nephropathy (DN) is one of the main complications associated with diabetes
mellitus. Persistently elevated blood glucose level drives histopathological changes in renal …

Background & aims Glycation, oxidative stress, and inflammation due to the elevation of
transforming growth factor-β1 (TGF-β1) participate in diabetic nephropathy (DN). Thus, we …

Background and Objective: Based on previous studies, inflammation and oxidative stress
play a crucial role in the pathophysiology of diabetic nephropathy. Therefore, we aimed to …

Oxidative damage, inflammation and apoptosis play significant roles in diabetic
nephropathy. Previous studies demonstrated anti‐inflammatory and anti‐oxidative effects of …

This study evaluated whether crocin, a bioactive component of saffron, has a protective
effect on kidney through reducing the oxidative stress and inflammatory response in aged …

This study aims to scrutinize the potential protective effect of diosmin and crocin against
cardio-vascular complications attributed to metabolic syndrome (MS). For 16 weeks, the rats …

Diabetes mellitus (DM) is a prevalent metabolic disorder with complications including
nephropathy, neuropathy, retinopathy and peripheral vascular disease. Crocin is a water …

Objective: Diabetic nephropathy is one of the most common microvascular complications of
diabetes mellitus that finally leads to complete loss of kidney function. Therefore, this study …

The reactive oxygen species take role in pathogenesis of many diseases including hypoxia,
hypercholesterolemia, atherosclerosis, nephropathy, hypertension, ischemia–reperfusion …